Caulophyllogenin(Synonyms: 儿茶酚)

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上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Caulophyllogenin (Synonyms: 儿茶酚)

Caulophyllogenin 是一种从 M. polimorpha 中提取的三萜皂苷。Caulophyllogenin 是 PPARγ 的部分激动剂，EC50 值为 12.6 μM。Caulophyllogenin 可用于研究 2 型糖尿病，肥胖症，代谢综合征和炎症。

Caulophyllogenin(Synonyms: 儿茶酚)

Caulophyllogenin Chemical Structure

CAS No. : 52936-64-8

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生物活性

Caulophyllogenin is a triterpene saponin extracted from M. polimorpha. Caulophyllogenin is a partial PPARγ agonist, with an EC50 of 12.6 μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic syndrome and inflammation[1][2].

IC50 & Target[1]

PPARγ

12.6 μM (EC50)

分子量

488.70

Formula

C30H48O5
CAS 号

52936-64-8
中文名称

儿茶酚
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Montanari R, et, al. Screening of saponins and sapogenins from Medicago species as potential PPARγ agonists and X-ray structure of the complex PPARγ/caulophyllogenin. Sci Rep. 2016 Jun 10; 6:27658.

    [2]. Zhang Y, et, al. Studies on cytotoxic triterpene saponins from the leaves of Aralia elata. Food Chem. 2013 May 1;138(1):208-13.