上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Levomenol (Synonyms: 没药醇; (-)-α-Bisabolol) 纯度: 98.35%
Levomenol ((-)-α-Bisabolol) 是一种单环倍半萜醇,具有抗氧化、抗炎和抗凋亡的作用。Levomenol 还具有神经保护作用,通过减少小鼠永久性局灶性脑缺血诱导的促炎标志物,防止神经元损伤和记忆缺陷。Levomenol 减轻三叉神经性疼痛啮齿动物模型的伤害性行为和中枢敏感性。
Levomenol Chemical Structure
CAS No. : 23089-26-1
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Levomenol 相关产品
•相关化合物库:
- Natural Product Library Plus
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- Immunology/Inflammation Compound Library
- Natural Product Library
- Terpenoids Library
- Orally Active Compound Library
- Traditional Chinese Medicine Monomer Library
- FDA Approved & Pharmacopeial Drug Library
- Neuroprotective Compound Library
- Food-Sourced Compound Library
生物活性 |
Levomenol ((-)-α-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol also has neuroprotective effects and prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Levomenol attenuates nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. Orally active[1][2]. |
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体内研究 (In Vivo) |
Levomenol ((-)-α-Bisabolol) (100-200 mg/kg; p.o.; one day before and 1 h after pMCAO; once daily for the following five day; Male Swiss mice) significantly reduces the infarcted area and neurological deficits caused by pMCAO[1]. pMCAO: permanent media cerebral artery occlusion. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
222.37 |
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Formula |
C15H26O |
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CAS 号 |
23089-26-1 |
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中文名称 |
没药醇;(-)-α-红没药醇 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (449.70 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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