上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Tenuigenin (Synonyms: 远志皂苷元; Senegenin) 纯度: 99.24%
Tenuigenin 是从中草药远志 (Polygala tenuifolia) 根中分离出来的主要活性成分。Tenuigenin 通过抑制 NF-κB 活化来预防金黄色葡萄球菌诱导的肺炎。
Tenuigenin Chemical Structure
CAS No. : 2469-34-3
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥600 | In-stock | |
10 mg | ¥1000 | In-stock | |
20 mg | ¥1800 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Tenuigenin 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Anti-Infection Compound Library
- Immunology/Inflammation Compound Library
- NF-κB Signaling Compound Library
- Stem Cell Signaling Compound Library
- Natural Product Library
- Anti-Aging Compound Library
- Antioxidants Compound Library
- Differentiation Inducing Compound Library
- Oxygen Sensing Compound Library
- Antibacterial Compound Library
- Medicine Food Homology Compound Library
- Terpenoids Library
- Pyroptosis Compound Library
- Traditional Chinese Medicine Monomer Library
- Anti-Breast Cancer Compound Library
- Anti-Pancreatic Cancer Compound Library
- Anti-Blood Cancer Compound Library
- Anti-Obesity Compound Library
- Transcription Factor Targeted Library
- Anti-Liver Cancer Compound Library
生物活性 |
Tenuigenin is a major active component isolated from the root of the Chinese herb Polygala tenuifolia. Tenuigenin protects against S.aureus-induced pneumonia by inhibiting NF-κB activation. Tenuigenin has anti-inflammatory effect[1]. |
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IC50 & Target[1] |
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体内研究 (In Vivo) |
Tenuigenin (2, 4, 8 mg/kg) significantly attenuates S.aureus-induced lung histopathological changes. Tenuigenin also inhibits lung wet/dry (W/D) ratio, and inflammatory cytokines TNF-α and IL-1β production in Male BALB/c mice[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
537.13 |
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Formula |
C30H45ClO6 |
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CAS 号 |
2469-34-3 |
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中文名称 |
远志皂苷元 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (186.17 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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