Vasopressin; 纯度: 99.68%
Vasopressin 是一种环状九肽,在下丘脑中枢合成。Vasopressin 参与下丘脑-垂体-肾上腺轴,并通过增强促肾上腺皮质激素释放因子的刺激作用调节垂体促肾上腺皮质激素分泌。Vasopressin 也可以作为一种神经递质,通过与特定的 G 蛋白偶联受体结合来发挥其作用。
Vasopressin Chemical Structure
CAS No. : 11000-17-2
规格 | 价格 | 是否有货 | 数量 |
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5 mg | ¥500 | In-stock | |
10 mg | ¥800 | In-stock | |
25 mg | ¥1200 | In-stock | |
50 mg | ¥2000 | In-stock | |
100 mg | ; | 询价 | ; |
200 mg | ; | 询价 | ; |
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Vasopressin 相关产品
•相关化合物库:
- Drug Repurposing Compound Library Plus
- FDA-Approved Drug Library Plus
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- FDA-Approved Drug Library
- Human Endogenous Metabolite Compound Library
- Drug Repurposing Compound Library
- FDA Approved & Pharmacopeial Drug Library
- Food-Sourced Compound Library
- Rare Diseases Drug Library
- Children’s Drug Library
- Peptide Library
生物活性 |
Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis, and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of corticotropin releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors[1][2][3]. |
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IC50 & Target |
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体外研究 (In Vitro) |
AVP (0.01 nM-1 μM) induces Ca2+ increase in Chinese hamster ovary cells expressing rat or human V1b receptors[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Vasopressin (0.03-0.3 μg/kg; i.p.) potentiates corticotropin release provoked by exogenous corticoliberin and increases corticotropin secretion subsequent to body water loss[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
1084.24 |
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Formula |
C46H65N15O12S2 |
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CAS 号 |
11000-17-2 |
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Sequence Shortening |
CYFQNCPR-NH2 (Disulfide Bridge: Cys1-Cys6) |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
DMSO : 100 mg/mL (92.23 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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