TLQP-21;
TLQP-21 是 VGF 衍生的具有内分泌和内分泌特性的肽,是一种强效的 G 蛋白偶联受体补体 3a 受体 1 (C3aR1) 激动剂 (EC50:小鼠 TLQP-21=10.3 μM;人 TLQP-21=68.8 μM)。TLQP-21 激活 C3aR1,从而诱导细胞内 Ca2+ 的增加。TLQP-21 可用于研究调节伤害感受和其他相关生理功能。
TLQP-21 Chemical Structure
CAS No. : 869988-94-3
规格 | 是否有货 | ||
---|---|---|---|
100 mg | ; | 询价 | ; |
250 mg | ; | 询价 | ; |
500 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
TLQP-21 的其他形式现货产品:
生物活性 |
TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca2+. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions[1][2]. |
||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
体外研究 (In Vitro) |
TLQP-21 is a peptide of 21 amino acids. At a dose of 3 μM TLQP-21 induces up to ~69% of the corresponding contraction promoted by acetylcholine[1][2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||||||
分子量 |
2432.75 |
||||||||||||||||||||
Formula |
C107H170N40O26 |
||||||||||||||||||||
CAS 号 |
869988-94-3 |
||||||||||||||||||||
Sequence |
Thr-Leu-Gln-Pro-Pro-Ala-Ser-Ser-Arg-Arg-Arg-His-Phe-His-His-Ala-Leu-Pro-Pro-Ala-Arg |
||||||||||||||||||||
Sequence Shortening |
TLQPPASSRRRHFHHALPPAR |
||||||||||||||||||||
运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||||||
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
||||||||||||||||||||
Solvent Solubility |
In Vitro:;
H2O Peptide Solubility and Storage Guidelines: 1.;;Calculate the length of the peptide. 2.;;Calculate the overall charge of the entire peptide according to the following table:
3.;;Recommended solution:
|
||||||||||||||||||||
参考文献 |
|