Gly-Arg-Gly-Asp-Ser; 纯度: 95.05%
Gly-Arg-Gly-Asp-Ser 是一种五肽,构成了糖蛋白,骨桥蛋白与细胞的结合域。
Gly-Arg-Gly-Asp-Ser Chemical Structure
CAS No. : 96426-21-0
规格 | 价格 | 是否有货 | 数量 |
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2 mg | ¥550 | In-stock | |
5 mg | ¥1100 | In-stock | |
10 mg | ¥1650 | In-stock | |
25 mg | ¥3300 | In-stock | |
50 mg | ; | 询价 | ; |
100 mg | ; | 询价 | ; |
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Gly-Arg-Gly-Asp-Ser 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptidomimetic Library
- Peptide Library
生物活性 |
Gly-Arg-Gly-Asp-Ser is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM[1] |
IC50 Target |
IC50: 5 μM (αvβ3), 6.5 μM (αvβ5)[2] |
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体外研究 (In Vitro) |
Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM[1]. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
490.47 |
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Formula |
C17H30N8O9 |
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CAS 号 |
96426-21-0 |
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Sequence |
Gly-Arg-Gly-Asp-Ser |
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Sequence Shortening |
GRGDS |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:;
DMSO : 100 mg/mL (203.89 mM; Need ultrasonic) H2O : 33.33 mg/mL (67.96 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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