天然产物 黄酮类 Flavonoids
Skullcapflavone II 纯度: 99.19%
Skullcapflavone II 是从黄芩中提取的黄酮类化合物,具有抗炎、抗菌作用。Skullcapflavone II 调节破骨细胞的分化、存活和功能。Skullcapflavone II 对 M. aurum 和M. bovis BCG 具有较强的抗菌活性。
Skullcapflavone II Chemical Structure
CAS No. : 55084-08-7
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
1 mg | ¥2000 | In-stock | |
5 mg | ¥5000 | In-stock | |
10 mg | 询价 | ||
50 mg | 询价 |
* Please select Quantity before adding items.
Skullcapflavone II 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Anti-Infection Compound Library
- Immunology/Inflammation Compound Library
- Natural Product Library
- Antibacterial Compound Library
- Phenols Library
- Traditional Chinese Medicine Monomer Library
- Flavonoids Library
生物活性 |
Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG[1][2]. |
---|---|
体外研究 (In Vitro) |
Skullcapflavone II inhibits osteoclastogenesis with decreased activation of MAPKs, Src, and cAMP response element-binding protein (CREB), which have been known to be redox sensitive. Skullcapflavone II decreases reactive oxygen species by scavenging them or activating nuclear factor-erythroid 2-related factor 2 (Nrf2), and its effects were partially reversed by hydrogen peroxide cotreatment or Nrf2 deficiency[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 (In Vivo) |
Skullcapflavone II, a potential bradykinin antagonist, reduces the major pathophysiological features of allergic asthma, at least in part by acting on TGF-β1/Smad signaling pathways[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
374.34 |
Formula |
C19H18O8 |
CAS 号 |
55084-08-7 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
参考文献 |
|