AKTide-2T TFA;
AKTide-2T TFA 是一个优良的体外 AKT 底物，可竞争性抑制组蛋白 H2B 磷酸化，其 Ki 值为 12 nM。AKTide-2T TFA 模拟 Akt 的最佳磷酸化序列，是一种抑制肽，是 S22 位置中缺失了野生型 AKTide。
AKTide-2T TFA Chemical Structure
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| 生物活性 |
AKTide-2T TFA is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T TFA mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position[1]. |
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| IC50 Target[1] |
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| 体外研究 (In Vitro) |
AKTide-2T TFA mimics the optimal phosphorylation sequence of Akt, and inhibits Akt phosphorylated Hsp27 by addition of 20 μM Akt inhibitory peptide[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
1829.89 |
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| Formula |
C76H115F3N28O22 |
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| Sequence |
Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser-Phe-Gly-His-His-Ala |
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| Sequence Shortening |
ARKRERTYSFGHHA |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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