D-JBD19 TFA

D-JBD19 TFA;

D-JBD19 TFA 是一种不可渗透性的多肽。D-JBD19 TFA 具有神经保护作用。

D-JBD19 TFAamp;;

D-JBD19 TFA Chemical Structure

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

D-JBD19 TFA is a non-permeable peptide[1]. D-JBD19 TFA has neuroprotective effects[2].

体外研究
(In Vitro)

D-JBD19 is a non-permeable cargo corresponding to dJNKi peptide[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Neuroprotective effects of D-JBD19 against middle cerebral artery occlusion (MCAO) as compared with D-JNKI1. 15.7 ng of either D-JBD19 or D-JNKI1 or 1570 ng of D-JBD19 are injected i.c.v. just after the ischemia. Animals were killed 24 h later. 100 times more D-JBD19 is needed to provide protection than with D-JNKI1[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

2364.58

Formula

C101H165F3N32O30

Sequence Shortening

DQSRPVQPFLNLTTPRKPR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Cardozo AK, et al. Cell-permeable peptides induce dose- and length-dependent cytotoxic effects. Biochim Biophys Acta. 2007 Sep;1768(9):2222-34.

    [2]. Vaslin A, et al. Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor. J Neurochem. 2011 Dec;119(6):1243-52.

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