iRGD peptide 1 TFA; 纯度: 98.34%
iRGD peptide 1 TFA 是一种原型肿瘤特异性组织穿透肽，可将药物深深地输送到血管外肿瘤组织中，并具有抗转移活性。
iRGD peptide 1 TFA Chemical Structure
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥600 | In-stock | |
| 5 mg | ￥1500 | In-stock | |
| 10 mg | ￥2400 | In-stock | |
| 50 mg | ; | 询价 | ; |
| 100 mg | ; | 询价 | ; |
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iRGD peptide 1 TFA 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Peptide Library
| 生物活性 |
iRGD peptide 1 TFA is the prototypic tumor-specific tissue-penetrating peptide, which delivers drugs deep into extravascular tumor tissue. iRGD peptide 1 TFA has anti-metastatic activity[1]. |
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| 体外研究 (In Vitro) |
iRGD peptide 1 (iRGD) inhibits migration of tumor cells and caused chemorepulsion in vitro in a CendR- and NRP-1-dependent manner. iRGD peptide 1 induces dramatic collapse of cellular processes and partial cell detachment, resulting in the repellent activity. These effects are prominently displayed when the cells are seeded on fibronectin, suggesting a role of CendR in functional regulation of integrins[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 体内研究 (In Vivo) |
iRGD peptide 1 (amino acid sequence: CRGDKGPDC; 4 μmol/kg; intravenous injection; every other day; for 21 days) potently inhibits spontaneous metastasis in mice[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
1064.08 |
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| Formula |
C37H60F3N13O16S2 |
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| Sequence |
Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys |
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| Sequence Shortening |
CRGDKGPDC |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Sealed storage, away from moisture
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture) |
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| 参考文献 |
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