KKI-5 (TFA)

发表于由

KKI-5 (TFA); 纯度: 99.93%

KKI-5 (TFA) 是一种特异性的组织激肽释放酶 (kallikrein) 抑制剂。KKI-5 (TFA) 可降低乳腺癌细胞浸润。

KKI-5 (TFA)amp;;

KKI-5 (TFA) Chemical Structure

规格 价格 是否有货 数量
1 mg ￥750 In-stock
5 mg ￥2250 In-stock
10 mg ￥3950 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

KKI-5 (TFA) 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

KKI-5 (TFA) is a specific inhibitor of tissue kallikrein. KKI-5 (TFA) can attenuate breast cancer cell invasion[1].

IC50 Target

Kallikrein[1]
分子量

887.90

Formula

C37H56F3N11O11
Sequence

Ac-Pro-Phe-Arg-Ser-Val-Gln-NH2
Sequence Shortening

Ac-PFRSVQ-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 9.09 mg/mL (10.24 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.1263 mL 5.6313 mL 11.2625 mL
5 mM 0.2253 mL 1.1263 mL 2.2525 mL
10 mM 0.1126 mL 0.5631 mL 1.1263 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Deshpande MS, et al. Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem. 1992 Aug 21;35(17):3094-102.