Ganoderic acid B(Synonyms: 灵芝酸B)

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Ganoderic acid B (Synonyms: 灵芝酸B) 纯度: 99.31%

Ganoderic acid B 是从灵芝中分离出的一种三萜化合物。Ganoderic acid B 能作为端粒酶抑制剂抑制 Epstein-Barr 病毒 (EBV) 抗原的活化。Ganoderic acid B 是一种 HIV-1 protease 的中等强度抑制剂。

Ganoderic acid B(Synonyms: 灵芝酸B)

Ganoderic acid B Chemical Structure

CAS No. : 81907-61-1

规格 价格 是否有货 数量
1 mg ¥1500 In-stock
5 mg ¥3750 In-stock
10 mg   询价  
50 mg   询价  

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Ganoderic acid B 相关产品

相关化合物库:

  • Natural Product Library Plus
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  • Metabolism/Protease Compound Library
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  • Lipid Compound Library
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  • Terpenoids Library
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  • Microbial Metabolite Library
  • Food-Sourced Compound Library

生物活性

Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease[1][2][3].

IC50 & Target

HIV-1 protease[3]

分子量

516.67

Formula

C30H44O7

CAS 号

81907-61-1

中文名称

灵芝酸B

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

DMSO : 50 mg/mL (96.77 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.9355 mL 9.6774 mL 19.3547 mL
5 mM 0.3871 mL 1.9355 mL 3.8709 mL
10 mM 0.1935 mL 0.9677 mL 1.9355 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Zhou S, et al. Triterpenes and Soluble Polysaccharide Changes in Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), During Fruiting Growth. Int J Med Mushrooms. 2018;20(9):859-871.

    [2]. Zheng DS, et al. Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors. Exp Ther Med. 2017 Oct;14(4):3273-3278.

    [3]. el-Mekkawy S, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry. 1998 Nov;49(6):1651-7.

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