Bombesin;(Synonyms: 蛙皮素) 纯度: 99.76%
Bombesin 是一种十四肽，在胃泌素释放和 G 蛋白受体活化中起重要作用。
Bombesin Chemical Structure
CAS No. : 31362-50-2
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥900 | In-stock | |
| 5 mg | ￥1800 | In-stock | |
| 10 mg | ￥3300 | In-stock | |
| 25 mg | ￥7100 | In-stock | |
| 50 mg | ; | 询价 | ; |
| 100 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Bombesin 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Peptide Library
| 生物活性 |
Bombesin, a tetradecapeptide, plays an important role in the release of gastrin and the activation of G-protein receptors[1]. |
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| 体外研究 (In Vitro) |
Bombesin is a tetradecapeptide with a COOH terminus ending in Gly-His-Leu-Met-NH2 and subsequently is shown to closely resemble two mammalian bombesin -related peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB)[1]. Bombesin is found to have stimulatory effects upon gastric and pancreatic secretions, release of gastrointestinal hormones, gallbladder contraction and bronchoconstriction. It is present in amphibian gastric endocrine cells, avian proventriculus endocrine cells and avian brain. In mammals it is present mainly in nerve cells and fibers. The only mammalian endocrine cell shown to date to have bombesin is the P-cell in fetal lung. Bombesin is also found in mammalian brain, with its highest concentration in the hypothalamus[2]. Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. In the presence of a low concentration (3.5%) of serum, bombesin stimulates 3T3 cell proliferation. In serum-free medium, bombesin induces DNA synthesis in the absence of any other added growth factor (IC50=1 nM)[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
1619.85 |
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| Formula |
C71H110N24O18S |
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| CAS 号 |
31362-50-2 |
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| Sequence |
{Glp}-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2 |
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| Sequence Shortening |
{Glp}-QRLGNQWAVGHLM-NH2 |
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| 中文名称 |
蛙皮素 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Protect from light
*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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| 溶解性数据 |
In Vitro:;
H2O : 1.43 mg/mL (0.88 mM; Need ultrasonic) |
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| 参考文献 |
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