SARS-CoV MPro-IN-2

天然产物醌类Quinones

SARS-CoV MPro-IN-2 

SARS-CoV MPro-IN-2 (compound 15) 是一种有效的 SARS-CoV-2 Mpro 抑制剂,IC50 sub> 值为 72.07 nM。病毒的主要蛋白酶 Mpro 作为加工病毒多蛋白的主要酶,有助于 SARS-CoV-2 在宿主细胞中的复制和转录,并已被定性为药物发现的有吸引力的靶点。SARS-CoV MPro-IN-2 具有研究 COVID-19 的潜力。

SARS-CoV MPro-IN-2

SARS-CoV MPro-IN-2 Chemical Structure

CAS No. : 81418-42-0

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

SARS-CoV MPro-IN-2 (compound 15) is a potent inhibitor of SARS-CoV-2 Mpro with an IC50 value of 72.07 nM. The main protease (Mpro) of the virus as the major enzyme processing viral polyproteins contributes to the replication and transcription of SARS-CoV-2 in host cells, and has been characterized as an attractive target in drug discovery. SARS-CoV MPro-IN-2 has the potential for the research of COVID-19[1].

分子量

230.22

Formula

C13H10O4

CAS 号

81418-42-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Cui J, et al. Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors. Eur J Med Chem. 2021;225:113789.