MMI-0100

MMI-0100;

MMI-0100 是一种细胞渗透性肽抑制剂,抑制丝裂原活化蛋白激酶活化蛋白激酶 II (MK2)。MMI-0100 在体内外减少内膜增生。MMI-0100 抑制 IL-6 表达而不影响 IL-8 表达。MMI-0100 抑制纤维化过程,例如静脉移植疾病。

MMI-0100amp;;

MMI-0100 Chemical Structure

CAS No. : 1039342-24-9

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5 mg ¥3000 In-stock
10 mg ¥4800 In-stock
25 mg ¥9500 In-stock
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生物活性

MMI-0100 is a cell-permeant peptide inhibitor of mitogen activated protein kinase activated protein kinase II (MK2). MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. MMI-0100 suppresses IL-6 expression without effect on IL-8 expression. MMI-0100 suppresses fibrotic processes such as vein graft disease[1].

分子量

2283.64

Formula

C98H171N37O26

CAS 号

1039342-24-9

Sequence Shortening

YARAAARQARAKALARQLGVAA

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Akihito Muto, et al. Inhibition of Mitogen Activated Protein Kinase Activated Protein Kinase II with MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. Vascul Pharmacol. Jan-Feb 2012;56(1-2):47-55.