荧光染料SiR-COOH

荧光染料Dye Reagents SiR-COOH;

SiR-COOH 可用于跟踪模型药物在 GFP 标记细胞中的位置。

SiR-COOH

SiR-COOH Chemical Structure

CAS No. : 1418275-26-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
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生物活性

SiR-COOH could be used to follow the intracellular location of the model therapeutic drug in GFP cells (Abs, 645 nm; Em, 676 nm)[1].

体外研究
(In Vitro)

SiR-COOH could be used to conjugated inhibitors such as UNC2025 (Mer inhibitor). SiR-COOH is especially useful for small-molecule probes: it exhibits bright photostable fluorescence at near-infrared wavelengths, which are ideal for imaging deep through tissue; fluorescence is robust across physiological environments with little toxicity; it is amenable to super-resolution microscopy; and it exhibits an optimal degree of hydrophilicity for live-cell imaging[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

472.61

Formula

C27H28N2O4Si

CAS 号

1418275-26-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Eunha Kim, et al. Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chem Commun (Camb). 2014 May 4;50(34):4504-7.

    [2]. Miles A Miller, et al. Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease. Chem Commun (Camb). 2017 Dec 19;54(1):42-45.https://pubmed.ncbi.nlm.nih.gov/29185561