天然产物 糖类和糖苷 Saccharides and Glycosides
Tunicamycin V;(Synonyms: Tunicamycin A) 纯度: ge;95.0%
Tunicamycin V (Tunicamycin A) 是一种核苷天然产物，可抑制细菌 phospho-N-acetylmuramyl-pentapeptide transferase (MraY)，IC50 为 0.35 μM。Tunicamycin V 具有抗菌活性。
Tunicamycin V Chemical Structure
CAS No. : 66054-36-2
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 1 mg | ￥11500 | In-stock | |
| 5 mg | ; | 询价 | ; |
| 10 mg | ; | 询价 | ; |
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| 生物活性 |
Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties[1][2]. |
IC50 Target |
IC50: 0.35 μM (phospho-N-acetylmuramyl-pentapeptide transferase (MraY))[1] |
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| 体外研究 (In Vitro) |
Tunicamycins are nucleoside natural products isolated from the fermentation broths of Streptomyces lysosuperficus in 1971 and exhibit a variety of biological properties including antibacterial, antiviral, antifungal, and antitumor activities. Tunicamycins strongly inhibit UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase, the enzyme responsible for the first N-acetylglucosamination of the N-linked glycopeptide in endothelial reticulum (ER)[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
830.92 |
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| Formula |
C38H62N4O16 |
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| CAS 号 |
66054-36-2 |
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| 中文名称 |
衣霉素V；衣霉素A |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 参考文献 |
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