Epimagnolin B(Synonyms: 表木兰脂素 B)

天然产物 天然产物苯丙素类 Phenylpropanoids

Epimagnolin B (Synonyms: 表木兰脂素 B)

Epimagnolin B 是从木兰中分离得到的一种具有抗炎活性的双环氧木质素。Epimagnolin B 抑制 LPS 激活的小胶质细胞中 NO 的产生。Epimagnolin B 具有抗过敏作用。

Epimagnolin B(Synonyms: 表木兰脂素 B)

Epimagnolin B Chemical Structure

CAS No. : 1134188-26-3

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生物活性

Epimagnolin B is a bisepoxylignan isolated from Magnolia fargesii, with anti-inflammatory activity and antiallergic effects. Epimagnolin B inhibits NO production in LPS-activated microglia. Epimagnolin B exhibited antiallergic effects[1][2].

体外研究
(In Vitro)

Epimagnolin B exhibits antiallergic effects without affecting the viability of BMMCs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

416.46

Formula

C23H28O7

CAS 号

1134188-26-3

中文名称

表木兰脂素 B

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Kim JY, et al. In vitro anti-inflammatory activity of lignans isolated from Magnolia fargesii. Bioorg Med Chem Lett. 2009 Feb 1;19(3):937-40.

    [2]. Xing Zhang, et al. Bioassay-guided isolation of bisepoxylignans from the flower buds of Magnolia biondii Pamp and their antiallergic effects.  RSC Advances. July 2017;7(54):34236-34243.