Bellidifolin(Synonyms: 龙胆山酮酚)

天然产物 黄酮类 Flavonoids

Bellidifolin (Synonyms: 龙胆山酮酚)

Bellidifolin 是从獐牙菜的茎中提取的一种呫吨酮 (xanthone) 化合物,具有保肝、降血糖、抗氧化、抗炎、抗肿瘤作用。Bellidifolin 能作为病毒蛋白 R (Vpr) 的抑制剂。

Bellidifolin(Synonyms: 龙胆山酮酚)

Bellidifolin Chemical Structure

CAS No. : 2798-25-6

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生物活性

Bellidifolin is a xanthone isolated from the stems of Swertia punicea, with hepatoprotective, hypoglycemic, anti-oxidation, anti-inflammatory and antitumor activities[1][2][3]. Bellidifolin also acts as a viral protein R (Vpr) inhibitor[4].

分子量

274.23

Formula

C14H10O6

CAS 号

2798-25-6

中文名称

龙胆山酮酚

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zhao ZY, et al. Protective effects of bellidifolin in hypoxia-induced in pheochromocytoma cells (PC12) and underlying mechanisms. J Toxicol Environ Health A. 2017;80(22):1187-1192.

    [2]. Zheng XY, et al. Two xanthones from Swertia punicea with hepatoprotective activities in vitro and in vivo. J Ethnopharmacol. 2014 May 14;153(3):854-63.

    [3]. Basnet P, et al. Bellidifolin: a potent hypoglycemic agent in streptozotocin (STZ)-induced diabetic rats from Swertia japonica. Planta Med. 1994 Dec;60(6):507-11.

    [4]. Woo SY, et al. Viral protein R inhibitors from Swertia chirata of Myanmar. J Biosci Bioeng. 2019 May 7.