天然产物 黄酮类 Flavonoids
Plantanone B (Synonyms: Kaempferol 3-O-rhamnosylgentiobioside)
Plantanone B 是一种中等抗氧化剂，IC50 为 169.8±5.2 μM。Plantanone B 具有显著的绵羊 COX-1 抑制活性和中等的 COX-2 抑制活性。Plantanone B 有研究炎症相关疾病的潜力。
Plantanone B Chemical Structure
CAS No. : 55780-30-8
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| 5 mg | 询价 | ||
| 10 mg | 询价 | ||
| 25 mg | 询价 |
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| 生物活性 |
Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM[1].Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively[1]..Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
756.66 |
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| Formula |
C33H40O20 |
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| CAS 号 |
55780-30-8 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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