Absinthin(Synonyms: 洋艾素)

发表于由

天然产物 黄酮类 Flavonoids

Absinthin (Synonyms: 洋艾素)

Absinthin 是一种结构独特的三萜类化合物，这是艾草苦味高的原因。Absinthin 是苦味受体 hTAS2R46 的一种激动剂，它通过 hTAS2R46 介导的受体特异性机制降低组胺诱导的细胞内 Ca2+ 升高。

Absinthin(Synonyms: 洋艾素)

Absinthin Chemical Structure

CAS No. : 1362-42-1

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生物活性

Absinthin is a structurally unique triterpene, and is responsible for the high bitter value of wormwood. Absinthin is an agonist of the bitter taste receptor hTAS2R46, which reduces cytosolic Ca2+-rises induced by histamine by a receptor-specific mechanism mediated by hTAS2R46[1][2][3].

分子量

496.64

Formula

C30H40O6
CAS 号

1362-42-1
中文名称

洋艾素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhang W, et al. Total synthesis of absinthin. J Am Chem Soc. 2005 Jan 12;127(1):18-9.

    [2]. Lachenmeier DW, et al. Absinthe–a review. Crit Rev Food Sci Nutr. 2006;46(5):365-77.

    [3]. Talmon M, et al. Absinthin, an agonist of the bitter taste receptor hTAS2R46, uncovers an ER-to-mitochondria Ca2+-shuttling event. J Biol Chem. 2019 Aug 16;294(33):12472-12482.