Triptoquinone B(Synonyms: (+)-Triptoquinone B)

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Triptoquinone B (Synonyms: (+)-Triptoquinone B)

Triptoquinone B ((+)-Triptoquinone B) 是一种倍半萜类生物碱，是一种白细胞介素 1 (interleukin-1) 抑制剂。 Triptoquinone B 可有效抑制人外周单核细胞的白细胞介素 1α 和 β 释放。

Triptoquinone B(Synonyms: (+)-Triptoquinone B)

Triptoquinone B Chemical Structure

CAS No. : 142937-50-6

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生物活性

Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2].

IC50 & Target[1]

IL-1

 

分子量

330.42

Formula

C20H26O4
CAS 号

142937-50-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Takaishi Y, et, al. Triptoquinone A and B novel interleukin-1 inhibitors from Tripterygium wilfordii var Regeli. Tetrahedron Letters. 1992 Nov; 33(47): 7177-7180.

    [2]. Wang XD, et, al. Terpene alkaloids from Tripterygium wilfordii. J Asian Nat Prod Res. 2005 Oct;7(5):755-9.