SiliaMetS DEAM:  Your last step toward uncompromised purity
Effectively eliminates trace metals and boronic acids from products

SiliaMetS DEAM is a versatile scavenger designed to remove trace metal or boronic acids from reaction intermediates or final APIs. 

Metals Removed

• Best scavenger for: Ag, Fe, Sn, Ti & Zn.
• Good scavenger for: Se.

Scavengers are our class of functionalized silica that exhibit ability to bond (that is, to “scavenge”) various metal compounds or organic molecules dissolve in solution. In organic chemistry, formation of new bonds is of utmost importance and for this to be achieved, cross-coupling reactions are among the most important processes.
Initially these reactions used simple Pd-catalysts. However, the need to carry out more challenging coupling reactions has resulted in the development of more advanced catalysts and the use of many different metals.

Our SiliaMetS DEAM is your best choice for the scavenging of Titanium (Ti), and is also very powerful for Zinc (Zn), Iron (Fe) and Silver (Ag). Apart from the pharmaceutical industry, metal scavengers such as DEAM can be used in many other industries that need to recover low levels of precious metals, such as mining, refining, manufacturing, etc.

SiliaMetS DEAM is a very versatile scavenger, as it is dual-purpose:  it also is a highly effective tool to remove excess boronic acids from non-aqueous solutions. Boronic acids are widely used in organic synthesis and for a vast range of biological, medicinal and synthetic applications, particularly Suzuki coupling reactions.

Our SiliaMetS DEAM is the first DEAM-silica supported on the market, and is produced in large scale in our state-of-the-art facilities.

Scheme 1. Scavenging of a boronic acid using Si-DEAM

Table 1

Table 2

Table 3

SPECIFICATION SHEET

Download the Specification Sheet

APPLICATION NOTE

Application Note for SiliaMetS DEAM