Chemerin-9 (149-157)

Chemerin-9 (149-157);

Chemerin-9 (149-157),是位于chemerin-9 149-157位的多肽 (YFPGQFAFS(157),与加工后的chemerin 的 C端相对应,保留了全蛋白绝大部分活性,与对chemerinR的激动作用有关。

Chemerin-9 (149-157)amp;;

Chemerin-9 (149-157) Chemical Structure

CAS No. : 676367-27-4

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1 mg ¥1200 询问价格 货期
5 mg ¥2500 询问价格 货期
10 mg ¥4500 询问价格 货期

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Chemerin-9 (149-157) 的其他形式现货产品:

Chemerin-9 (149-157) (TFA)

生物活性

Chemerin-9 (149-157), the nonapeptide (149)YFPGQFAFS(157) (chemerin-9), corresponding to the C terminus of processed chemerin, retains most of the activity of the full-size protein, with regard to agonism toward the chemerinR[1].

分子量

1063.16

Formula

C54H66N10O13

CAS 号

676367-27-4

Sequence Shortening

YFPGQFAFS

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Wittamer V, et al. The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency. J Biol Chem. 2004 Mar 12;279(11):9956-62.

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