Protein Kinase C (19-36)

Protein Kinase C (19-36);

Protein Kinase C (19-36) 是蛋白激酶 C (PKC) 的伪底物肽抑制剂,其IC50 值为 0.18 μM。Protein Kinase C (19-36) 有效减缓血管增生和肥大,抑制葡萄糖诱导的利钠肽受体反应。

Protein Kinase C (19-36)amp;;

Protein Kinase C (19-36) Chemical Structure

CAS No. : 113731-96-7

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生物活性

Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response[1].

IC50 Target

IC50: 0.18 μM (protein kinase C)[1].

分子量

2151.48

Formula

C93H159N35O24

CAS 号

113731-96-7

Sequence

Arg-PheAla-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn

Sequence Shortening

RFARKGALRQKNVHEVKN

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Yasunari K, et al. Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration. Hypertension. 1996 Aug;28(2):159-68.