Xenopsin TFA(Synonyms: 爪蟾肽三氟乙酸盐)

Xenopsin TFA;(Synonyms: 爪蟾肽三氟乙酸盐)

Xenopsin TFA 是一种来自非洲爪蟾皮肤的神经降压素样八肽。Xenopsin TFA 抑制胃泌素刺激的胃酸分泌。

Xenopsin TFAamp;;(Synonyms: 爪蟾肽三氟乙酸盐)

Xenopsin TFA Chemical Structure

规格 是否有货
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250 mg ; 询价 ;
500 mg ; 询价 ;

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Xenopsin TFA 的其他形式现货产品:

Xenopsin

生物活性

Xenopsin TFA, a neurotensin-like octapeptide from Xenopus laevis skin[1]. Xenopsin TFA is an inhibitor of Tetragastrin stimulated gastric acid secretion[2].

体外研究
(In Vitro)

Xenopsin is a biologically active octapeptide found in skin extracts from Xenopus laevis[1]. Xenopsin produces a significant inhibition of tetragastrin-stimulated gastric acid output[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1094.19

Formula

C49H74F3N13O12

Sequence

{Glp}-Gly-Lys-Arg-Pro-Trp-Ile-Leu

Sequence Shortening

{Glp}-GKRPWIL

中文名称

爪蟾肽三氟乙酸盐

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Sures I, et al. Xenopsin: the neurotensin-like octapeptide from Xenopus skin at the carboxyl terminus of its precursor. Proc Natl Acad Sci U S A. 1984 Jan;81(2):380-4.

    [2]. Zinner MJ, et al. Effect of xenopsin on blood flow, hormone release, and acid secretion. Am J Physiol. 1982 Sep;243(3):G195-9.

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