β-Cyclodextrin(Synonyms: β-环糊精)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

β-Cyclodextrin;(Synonyms: β-环糊精) 纯度: ge;98.0%

β-Cyclodextrin 是一种环状多糖，由 α-D-吡喃型葡萄糖单元通过 α-(1,4) 糖苷键连接而成。β-Cyclodextrin 通常用于增强药物的溶解度。β-Cyclodextrin 具有抗流感病毒 H1N1 的活性。

β-Cyclodextrin(Synonyms: β-环糊精)

β-Cyclodextrin Chemical Structure

CAS No. : 7585-39-9

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in Water ￥500 In-stock
500 mg ￥400 In-stock
1 g ￥500 In-stock
5 g ; 询价 ;
10 g ; 询价 ;

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生物活性

β-Cyclodextrin is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds. β-Cyclodextrin has often been used to enhance the solubility of drugs. β-Cyclodextrin has anti-influenza virus H1N1 activities.

体外研究
(In Vitro)

β-Cyclodextrin (Beta-cyclodextrin; β-CD) is a cyclic polysaccharide composed of seven units of glucose (α-D-glucopyranose) linked by α-(1,4) type bonds, which presents a hydrophilic external surface and a hydrophobic internal cavity[1]. In the pharmaceutical industry, β-Cyclodextrin (β-CD) has often been used to enhance the solubility of drugs, such as indomethacin, naringin, celecoxib, and citric acid[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1134.98

Formula

C42H70O35
CAS 号

7585-39-9
中文名称

β-环糊精
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 38.75 mg/mL (34.14 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8811 mL 4.4054 mL 8.8107 mL
5 mM 0.1762 mL 0.8811 mL 1.7621 mL
10 mM 0.0881 mL 0.4405 mL 0.8811 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Campos EVR, et al. Chitosan nanoparticles functionalized with β-cyclodextrin: a promising carrier for botanicalpesticides. Sci Rep. 2018 Feb 1;8(1):2067.

    [2]. Cui L, et al. Effect of β-cyclodextrin complexation on solubility and enzymatic conversion of naringin. Int J Mol Sci. 2012 Nov 5;13(11):14251-61.

    [3]. Goncharova EP, et al. A Novel Sulfonated Derivative of β-Cyclodextrin Effectively Inhibits Influenza A Virus Infection in vitro and in vivo. Acta Naturae. 2019 Jul-Sep;11(3):20-30.