Gomisin D(Synonyms: 戈米辛 D)

天然产物 天然产物苯丙素类 Phenylpropanoids

Gomisin D (Synonyms: 戈米辛 D)

Gomisin D 是一种从五味子 (Fructus Schisandra) 中分离出来的木脂素化合物,潜在的抗糖尿病药和抗阿尔茨海默病药。 Gomisin D 可以抑制 UDP-葡糖醛酸基转移酶活性,清除 ABTS(+) 自由基。 Gomisin D 被用作生脉散和参芪降糖颗粒的质量标志物。

Gomisin D(Synonyms: 戈米辛 D)

Gomisin D Chemical Structure

CAS No. : 60546-10-3

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生物活性

Gomisin D, a lignan compound isolated from Fructus Schisandra, is a potential antidiabetic and anti-Alzheimer’s agent. Gomisin D inhibits UDP-Glucuronosyltransferases activity and scavenges ABTS(+) radicals. Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule[1].

IC50 & Target

UDP-Glucuronosyltransferases[1]

分子量

530.56

Formula

C28H34O10

CAS 号

60546-10-3

中文名称

戈米辛 D

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Zheng X, et al. A Rapid UPLC-MS Method for Quantification of Gomisin D in Rat Plasma and Its Application to a Pharmacokinetic and Bioavailability Study. Molecules. 2019 Apr 10;24(7).