Isoglycycoumarin

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天然产物 黄酮类 Flavonoids

Isoglycycoumarin 

Isoglycycoumarin 是从Glycyrrhiza uralensis 根中提取的黄酮类化合物。Isoglycycoumarin 是一种高度选择性的人细胞色素 P450 2A6 (CYP2A6) 探针。

Isoglycycoumarin

Isoglycycoumarin Chemical Structure

CAS No. : 117038-82-1

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生物活性

Isoglycycoumarin is a flavonoid isolated from the roots of Glycyrrhiza uralensis. Isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6 (CYP2A6)[1][2].

IC50 & Target

P450 2A6[2]
分子量

368.38

Formula

C21H20O6
CAS 号

117038-82-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Li S, et al. Prenylflavonoids from Glycyrrhiza uralensis and their protein tyrosine phosphatase-1B inhibitory activities. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5398-401.

    [2]. Wang Q, et al. The prenylated phenolic natural product isoglycycoumarin is a highly selective probe for human cytochrome P450 2A6. Eur J Pharm Sci. 2017 Nov 15;109:472-479.