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Myrciacetin

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天然产物 黄酮类 Flavonoids

Myrciacetin 

Myrciacetin 是一种黄酮类化合物。Myrciacetin 对大鼠晶状体醛糖还原酶 (aldose reductase) 有抑制作用，IC50 为 13 μM 。

Myrciacetin

Myrciacetin Chemical Structure

CAS No. : 203734-35-4

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生物活性

Myrciacetin is a flavonoid from Rhododendron dauricum. Myrciacetin is against rat lens aldose reductase with an IC50 of 13 μM[1].

IC50 & Target

IC50: aldose reductase[1]
体外研究
(In Vitro)

Aldose reductase catalizes the reduction of glucose to sorbitol in the polyol pathway and is related to chronic complications such as peripheral neuropathy, retinopathy, and cataracts[1].
Myrciacetin shows potent inhibitory activity against rat lens aldose reductase with an IC50 of 13 μM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

316.31

Formula

C17H16O6
CAS 号

203734-35-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Hisashi MATSUDA,et al. Antidiabetic Principles of Natural Medicines. V.1) Aldose Reductase Inhibitors from Myrcia multiflora DC. (2): Structures of Myrciacitrins III, IV, and V. N Chem. Pharm. Bull. 50(3) 429—431 (2002)

    [2]. Xin-Wei Lou, et al. Identification and characterization of three new flavonoids from Rhododendron dauricum. Chin J Nat Med

3′,4′,5′,5,6,7-Hexamethoxyflavone

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天然产物 黄酮类 Flavonoids

3′,4′,5′,5,6,7-Hexamethoxyflavone 

3′,4′,5′,5,6,7-Hexamethoxyflavone 是一种具有抗原生动物活性的黄酮类化合物。3′,4′,5′,5,6,7-Hexamethoxyflavone 抑制 trypanosoma bruceirhodesiense，IC50 值为 21.3 μM (8.58 g/mL)。

3′,4′,5′,5,6,7-Hexamethoxyflavone

3′,4′,5′,5,6,7-Hexamethoxyflavone Chemical Structure

CAS No. : 29043-07-0

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生物活性

3′,4′,5′,5,6,7-Hexamethoxyflavone is a flavonoid with antiprotozoal activity. 3′,4′,5′,5,6,7-Hexamethoxyflavone inhibits trypanosoma bruceirhodesiense with IC50 of 21.3 μM (8.58 g/mL)[1].

分子量

402.39

Formula

C21H22O8
CAS 号

29043-07-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Nour AM, et al. The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. J Ethnopharmacol. 2010;129(1):127-130.

Violanone

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天然产物 黄酮类 Flavonoids

Violanone 

Violanone 是一种异黄烷酮化合物，可以抑制微管蛋白聚合。Violanone 还表现出对 A. aegypti 的杀幼虫活性。

Violanone

Violanone Chemical Structure

CAS No. : 52250-38-1

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生物活性

Violanone, an isoflavanone compound, can inhibit tubulin polymerization. Violanone also exhibits larvicidal activity against A. aegypti[1][2].

IC50 & Target

Microtubule/Tubulin[1]
体外研究
(In Vitro)

Violanone inhibitS the microtubule assembly by 16%[1].
Violanone shows larvicidal activity against A. aegypti, with an LC50 of 157.55 µg/mL[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

316.31

Formula

C17H16O6
CAS 号

52250-38-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Deesamer S, et, al. Synthesis and biological evaluation of isoflavone analogues from Dalbergia oliveri. Tetrahedron. 2007 Dec 24; 63(52): 12986-12993.

    [2]. Bezerra-Silva PC, et, al. Extract of Bowdichia virgilioides and maackiain as larvicidal agent against Aedes aegypti mosquito. Exp Parasitol. 2015 Jun;153:160-4.

3-Aminopropyltriethoxysilane

发表于由

生化分析试剂 Biochemical Assay Reagents
3-Aminopropyltriethoxysilane;

3-Aminopropyltriethoxysilane 是一种常用的生物分子固定在硅和硅衍生物上的方法，如氮化硅 (Si3N4)。

3-Aminopropyltriethoxysilane

3-Aminopropyltriethoxysilane Chemical Structure

CAS No. : 919-30-2

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100 mg ￥350 In-stock
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3-Aminopropyltriethoxysilane 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

3-Aminopropyltriethoxysilane is a common method for biomolecule immobilization on silicon and silicon derivatives such as silicon nitride (Si3N4)[1].

分子量

221.37

Formula

C9H23NO3Si
CAS 号

919-30-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
参考文献

  • [1]. Saengdee P, et al. Optimization of 3-aminopropyltriethoxysilane functionalization on silicon nitride surface for biomolecule immobilization. Talanta. 2020;207:120305.

Kushenol C

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天然产物 黄酮类 Flavonoids

Kushenol C 

Kushenol C 是从苦参根中分离出来的，具有抗炎和抗氧化的作用。Kushenol C 抑制 BACE1 的 IC50 值为 5.45 µM。

Kushenol C

Kushenol C Chemical Structure

CAS No. : 99119-73-0

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生物活性

Kushenol C, isolated from the roots of Sophora flavescens, shows anti-Inflammatory and anti-oxidative stress activities. Kushenol C inhibits BACE1 (β-site APP cleaving enzyme 1) with an IC50 of 5.45 µM[1][2].

体外研究
(In Vitro)

Kushenol C dose-dependently suppresses the production of inflammatory mediators, including NO, PGE2, IL-6, IL1β, MCP-1, and IFN-β in LPS-stimulated RAW264.7 macrophages. Kushenol C (50-100 µM;) significantly decreases the phosphorylation of both STAT1 molecules and STAT6 in a dose-dependent manner in LPS-stimulated RAW264.7 cells[1].
Kushenol C upregulates the expression of HO-1 and its activities in the LPS-stimulated RAW264.7 macrophages. In HaCaT cells, Kushenol C prevents DNA damage and cell death by upregulating the endogenous antioxidant defense system involving glutathione, superoxide dismutase, and catalase, which prevents reactive oxygen species production from tert-butyl hydroperoxide (tBHP)-induced oxidative stress in HaCaT cells[1].
Kushenol C inhibits BChE and AChE with IC50s of 54.86 and 33.13 µM[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

438.47

Formula

C25H26O7
CAS 号

99119-73-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Cho BO, et al. In vitro Anti-Inflammatory and Anti-Oxidative Stress Activities of Kushenol C Isolated from the Roots of Sophoraflavescens. Molecules. 2020;25(8):1768. Published 2020 Apr 12.

    [2]. Jung HA, et al. Selective inhibition of prenylated flavonoids from Sophora flavescens against BACE1 and cholinesterases. Am J Chin Med. 2010;38(2):415-429.

Glomeratose A

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天然产物 天然产物苯丙素类 Phenylpropanoids

Glomeratose A  纯度: 99.79%

Glomeratose A 是一种乳酸脱氢酶 lactate dehydrogenase 抑制剂，是从远志 Polygala tenuifolia 分离的。

Glomeratose A

Glomeratose A Chemical Structure

CAS No. : 202471-84-9

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5 mg ￥3430 In-stock
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Glomeratose A 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Glycoside Compound Library
  • Glycolysis Compound Library
  • Anti-Cancer Metabolism Compound Library
  • Glucose Metabolism Compound Library

生物活性

Glomeratose A is a lactate dehydrogenase inhibitor, isolated from Polygala tenuifolia[1].

IC50 & Target

IC50: Lactate dehydrogenase[1]
分子量

562.52

Formula

C24H34O15
CAS 号

202471-84-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Li S, et al. Bioactivity screening, extraction, and separation of lactate dehydrogenase inhibitors from Polygala tenuifolia Willd. based on a hyphenated strategy. J Sep Sci. 2017 Mar;40(6):1385-1395.

Glicoricone

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天然产物 黄酮类 Flavonoids

Glicoricone 

Glicoricone 是一种从甘草中分离出来的酚类化合物。Glicoricone 是单胺氧化酶 (MAO) 的抑制剂，IC50 为 140 μM。Glicoricone 可与雌激素受体 (ER) 结合并显示出雌激素拮抗剂活性。

Glicoricone

Glicoricone Chemical Structure

CAS No. : 161099-37-2

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生物活性

Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity[1][2].

IC50 & Target

IC50: 140 μM (monoamine oxidase)[1]
分子量

368.38

Formula

C21H20O6
CAS 号

161099-37-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Hatano T, et, al. Phenolic constituents of licorice. III. Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase. Chem Pharm Bull (Tokyo). 1991 May;39(5):1238-43.

    [2]. Boonmuen N, et, al. Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids. 2016 Jan;105:42-9.

ADA

发表于由

生化分析试剂 Biochemical Assay Reagents
ADA; 纯度: ge;97.0%

ADA 是一种生物缓冲液。ADA 可以用作螯合剂。

ADA

ADA Chemical Structure

CAS No. : 26239-55-4

规格 价格 是否有货 数量
10;mM;*;1 mL in Water ￥500 询价
500 mg ￥500 In-stock
1 g ; 询价 ;
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ADA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus

生物活性

ADA is a biological buffer[1]. ADA can serve as a chelator[2].

分子量

190.15

Formula

C6H10N2O5
CAS 号

26239-55-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 5 mg/mL (26.30 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.2590 mL 26.2950 mL 52.5901 mL
5 mM 1.0518 mL 5.2590 mL 10.5180 mL
10 mM 0.5259 mL 2.6295 mL 5.2590 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. T Minami, et al. Identification of metallothionein isoforms with capillary zone electrophoresis using a polyacrylamide-coated tube. J Chromatogr B Biomed Appl. 1996 Oct 25;685(2):353-9.

    [2]. Birte M Gerken, et al. Tweezing-adsorptive bubble separation. Analytical method for the selective and high enrichment of metalloenzymes. Anal Chem. 2005 Oct 1;77(19):6113-7.

Peritassine A

发表于由

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Peritassine A 

Peritassine A 是可从Tripterygium wilfordii Hook. f. 分离得到的一种生物碱，具有抗 HIV 活性。

Peritassine A

Peritassine A Chemical Structure

CAS No. : 262601-67-2

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生物活性

Peritassine A, an alkaloid that could be isolated from Tripterygium wilfordii Hook. f., possesses anti-HIV activity[1][2].

分子量

791.75

Formula

C37H45NO18
CAS 号

262601-67-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Haoyu Ye, et al. Preparative separation of a terpenoid and alkaloids from Tripterygium wilfordii Hook. f. using high-performance counter-current chromatography. Comparison of various elution and operating strategies. J Chromatogr A. 2008 Dec 12;1213(2):145-53.

    [2]. H Duan, et al. Sesquiterpene alkaloids from Tripterygium hypoglaucum and Tripterygium wilfordii: a new class of potent anti-HIV agents. J Nat Prod. 2000 Mar;63(3):357-61.

Morusignin L

发表于由

天然产物 黄酮类 Flavonoids

Morusignin L 

Morusignin L 是一种具有抗骨质疏松症活性的化合物。

Morusignin L

Morusignin L Chemical Structure

CAS No. : 149733-95-9

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生物活性

Morusignin L is an active compound that shows anti-osteoporosis activities[1][2].

分子量

438.47

Formula

C25H26O7
CAS 号

149733-95-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Li M, et, al. Two novel compounds from the root bark of Morus alba L. Nat Prod Res. 2018 Jan;32(1):36-42.

    [2]. Lin B, et, al. Rapid, microwave-accelerated synthesis and anti-osteoporosis activities evaluation of Morusin scaffolds and Morusignin L scaffolds. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2389-2396.