上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Taraxerol acetate (Synonyms: 醋酸蒲公英霜)
Taraxerol acetate 是 COX-1 和 COX-2 抑制剂， IC50 值分别为 116.3 μM 和 94.7μM。Taraxerol acetate 具有抗癌作用并诱导细胞凋亡(apoptosis)。
Taraxerol acetate Chemical Structure
CAS No. : 2189-80-2
| 规格 | 价格 | 是否有货 | |
|---|---|---|---|
| 1 mg | ￥2860 | 询问价格 & 货期 | |
| 5 mg | ￥8570 | 询问价格 & 货期 | |
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| 生物活性 |
Taraxerol acetate is a COX-1 and COX-2 inhibitor with IC50 values of 116.3 μM and 94.7 μM, respectively. Taraxerol acetate the has the anticancer potential and induces cell apoptosis[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
Taraxerol acetate(10-150 µM; 24 or 48 hours) induces a dose- and time-dependent cytotoxic effects in the U87 cells, exhibits IC50 values of 34.2 and 28.4 µM, at 24 and 48 h, respectively[2]. Taraxerol acetate(10, 50 and 150 µM; 24 hours) induces cell apoptosis, the percentage of apoptotic cells increased from 7.3% in the control cells, to 16.1, 44.1 and in the 10, 50 and 150 µM taraxerol acetate-treated cells, respectively. Furthermore, taraxerol acetate treatment led to sub-G1 cell cycle arrest with a corresponding decrease in the number of S-phase cells[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
468.75 |
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| Formula |
C32H52O2 |
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| CAS 号 |
2189-80-2 |
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| 中文名称 |
醋酸蒲公英霜 |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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