Asperaculane B

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Asperaculane B 

Asperaculane B 是一种抗恶性疟原虫传播的真菌代谢产物, IC50为 7.89 µM。Asperaculane B 还抑制 IC50 为 3 µM 的无性恶性疟原虫的发育,并且对人类细胞无毒。

Asperaculane B

Asperaculane B Chemical Structure

CAS No. : 2378379-27-0

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生物活性

Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC50 of 7.89 µM. Asperaculane B also inhibits the development of asexual P. falciparum with IC50 of 3 µM, and it is nontoxic to human cells[1].

IC50 & Target[1]

Microbial Metabolite

 

体外研究
(In Vitro)

Asperaculane B is a new dual-functional antimalarial lead that has the potential to treat malaria and block malaria transmission[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

236.31

Formula

C14H20O3

CAS 号

2378379-27-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Niu G, et al. Fungal Metabolite Asperaculane B Inhibits Malaria Infection and Transmission. Molecules. 2020;25(13):3018. Published 2020 Jul 1.