[Des-Arg9]-Bradykinin(Synonyms: [Des-Arg9]-缓激肽)

[Des-Arg9]-Bradykinin;(Synonyms: [Des-Arg9]-缓激肽)

[Des-Arg9]-Bradykinin 是一种Bradykinin (B1) 受体激动剂,对 B1 受体选择性比B2 受体高。

[Des-Arg9]-Bradykininamp;;(Synonyms: [Des-Arg9]-缓激肽)

[Des-Arg9]-Bradykinin Chemical Structure

CAS No. : 15958-92-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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[Des-Arg9]-Bradykinin 的其他形式现货产品:

[Des-Arg9]-Bradykinin acetate

生物活性

[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.

IC50 Target

Bradykinin (B1) receptor[1]

体外研究
(In Vitro)

The B2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B1 receptor mediates the action of [Des-Arg9]-Bradykinin (des-Arg9-BK) and Lys-des-Arg Arg9-BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

904.02

Formula

C44H61N11O10

CAS 号

15958-92-6

Sequence

Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

Sequence Shortening

RPPGFSPF

中文名称

[Des-Arg9]-缓激肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.