GRK2i

发表于2023年11月1日由Whatman官网

GRK2i;

GRK2i 是一种 Gβγ 抑制肽，可选择性地阻止 Gβγ 介导的信号传导。GRK2i 对应于 GRK2（G 蛋白偶联受体激酶 2）的 Gβγ 结合域。

GRK2iamp;;

GRK2i Chemical Structure

CAS No. : 148505-03-7

规格		是否有货
100 mg	;	询价	;
250 mg	;	询价	;
500 mg	;	询价	;

* Please select Quantity before adding items.

生物活性	GRK2i is a Gβγ-inhibitory peptide that selectively prevents Gβγ-mediated signaling. GRK2i corresponds to the Gβγ-binding domain of GRK2 (G-protein-coupled receptor kinase 2)^[1].
IC₅₀ Target	Gβγ
体外研究 (In Vitro)	GRK2i (5 μM) inhibits neurite formation, disrupts microtubules, and induces neurite damag in PC12 cells^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	3484.08
Formula	C₁₅₃H₂₅₆N₅₀O₄₁S
CAS 号	148505-03-7
Sequence Shortening	WKKELRDAYREAQQLVQRVPKMKNKPRS
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Jorge A Sierra-Fonseca, et al. Nerve growth factor induces neurite outgrowth of PC12 cells by promoting Gβγ-microtubule interaction. BMC Neurosci. 2014 Dec 31;15:132.