Fmoc-Ala-Glu-Asn-Lys-NH2; 纯度: 98.04%
Fmoc-Ala-Glu-Asn-Lys-NH2 是一种选择性天冬酰胺内肽酶 AEP 抑制肽，可抑制淀粉样前体蛋白 APP 裂解。AEP是一种 pH 值控制的半胱氨酸蛋白酶，在衰老过程中被激活并介导 APP 蛋白水解过程。
Fmoc-Ala-Glu-Asn-Lys-NH2 Chemical Structure
CAS No. : 220701-06-4
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 5 mg | ￥1350 | In-stock | |
| 10 mg | ￥2350 | In-stock | |
| 50 mg | ; | 询价 | ; |
| 100 mg | ; | 询价 | ; |
* Please select Quantity before adding items.
Fmoc-Ala-Glu-Asn-Lys-NH2 相关产品
bull;相关化合物库:
- Bioactive Compound Library Plus
- Neuronal Signaling Compound Library
- Anti-Alzheimer’s Disease Compound Library
- Peptide Library
| 生物活性 |
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing[1]. |
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 体外研究 (In Vitro) |
Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
||||||||||||||||
| 分子量 |
681.74 |
||||||||||||||||
| Formula |
C33H43N7O9 |
||||||||||||||||
| CAS 号 |
220701-06-4 |
||||||||||||||||
| Sequence Shortening |
{Fmoc}-AENK-NH2 |
||||||||||||||||
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||||||
| 储存方式 |
Protect from light, stored under nitrogen
*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light, stored under nitrogen) |
||||||||||||||||
| 溶解性数据 |
In Vitro:;
DMSO : 100 mg/mL (146.68 mM; ultrasonic and warming and heat to 80°C) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
||||||||||||||||
| 参考文献 |
|