N-Acetylneuraminic acid(Synonyms: 唾液酸; NANA; Lactaminic acid)

天然产物 糖类和糖苷 Saccharides and Glycosides

N-Acetylneuraminic acid;(Synonyms: 唾液酸; NANA; Lactaminic acid) 纯度: ge;98.0%

N-Acetylneuraminic酸是一个在细胞膜的糖蛋白和哺乳细胞神经节甘脂的糖脂上普遍存在的唾液酸单糖,在神经传递, 白细胞血管渗出,病毒或细菌感染起着生物作用。

N-Acetylneuraminic acid(Synonyms: 唾液酸; NANA;  Lactaminic acid)

N-Acetylneuraminic acid Chemical Structure

CAS No. : 131-48-6

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in Water ¥550 In-stock
100 mg ¥500 In-stock
1 g ¥700 In-stock
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10 g ; 询价 ;

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N-Acetylneuraminic acid 相关产品

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生物活性

N-Acetylneuraminic acid is a nine-carbon, sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids such as gangliosides in mammalian cells. Studies suggest that N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition.

IC50 Target

Human Endogenous Metabolite

;

分子量

309.27

Formula

C11H19NO9

CAS 号

131-48-6

中文名称

唾液酸;N-乙酰神经氨酸;醋纽拉酸;N-乙酰涎酸;氧-唾液酸;N-乙酰-神经氨 (糖) 酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20deg;C, stored under nitrogen

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (stored under nitrogen)

溶解性数据
In Vitro:;

H2O : ≥ 100 mg/mL (323.34 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.2334 mL 16.1671 mL 32.3342 mL
5 mM 0.6467 mL 3.2334 mL 6.4668 mL
10 mM 0.3233 mL 1.6167 mL 3.2334 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403.

    [2]. Kiefel MJ, et al. Synthesis and biological evaluation of N-acetylneuraminic acid-based rotavirus inhibitors. J Med Chem. 1996 Mar 15;39(6):1314-20.