Damulin A(Synonyms: 达木林A)

天然产物糖类和糖苷 Saccharides and Glycosides

Damulin A;(Synonyms: 达木林A)

Damulin A 是 G. pentaphyllum 中发现的一种具有抗癌活性的皂苷。

Damulin A Chemical Structure

CAS No. : 1202868-74-3

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生物活性	Damulin A is a saponin found in G. pentaphyllum with anti-cancer activities^[1].
体外研究 (In Vitro)	Damulin A has anti-cancer activities and shows stronger cytotoxicity against A549 cells with an IC₅₀ value of 59.2 μM^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	783.00
Formula	C₄₂H₇₀O₁₃
CAS 号	1202868-74-3
中文名称	达木林A
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Wei-Ye Cui, et al. Dammarane-type saponins from Gynostemma pentaphyllum and their cytotoxicities. Nat Prod Res. 2020 Feb 10;1-9.

Damulin B(Synonyms: 达木林B)

天然产物糖类和糖苷 Saccharides and Glycosides

Damulin B;(Synonyms: 达木林B)

Damulin B 是一种皂苷类化合物，可存在于绞股蓝中。Damulin B 能诱导细胞凋亡 (apoptosis)，并在体外具有的抗癌活性。

Damulin B Chemical Structure

CAS No. : 1202868-75-4

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生物活性	Damulin B is a dammarane-type saponin found in Gynostemma pentaphyllum.Damulin B can induce cell apoptosis and has anti-cancer activities in vitro^[1]^[2].
分子量	783.00
Formula	C₄₂H₇₀O₁₃
CAS 号	1202868-75-4
中文名称	达木林B
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Shao-Fang Xing, et al. Inhibitory Effect of Damulin B from Gynostemma pentaphyllum on Human Lung Cancer Cells. Planta Med. 2019 Mar;85(5):394-405. [2]. Phi Hung Nguyen, et al. New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum. Bioorg Med Chem. . 2011 Nov 1;19(21):6254-60.