Rubiadin(Synonyms: 茜草素)

天然产物醌类Quinones

Rubiadin (Synonyms: 茜草素) 纯度: 99.29%

Rubiadin 是一种从茜草提取的二羟基蒽醌。Rubiadin 具有有效的抗氧化剂活性。

Rubiadin(Synonyms: 茜草素)

Rubiadin Chemical Structure

CAS No. : 117-02-2

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Rubiadin 相关产品

相关化合物库:

  • Natural Product Library Plus
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  • Immunology/Inflammation Compound Library
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  • Traditional Chinese Medicine Monomer Library

生物活性

Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity[1].

分子量

254.24

Formula

C15H10O4

CAS 号

117-02-2

中文名称

茜草素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献
  • [1]. Tripathi YB, et al. Rubiadin, a new antioxidant from Rubia cordifolia.Indian J Biochem Biophys. 1997 Jun;34(3):302-6.

Rubiadin-1-methyl ether

天然产物醌类Quinones

Rubiadin-1-methyl ether 

Rubiadin-1-methyl ether 是巴戟天中的蒽醌类化合物,可抑制破骨细胞性骨吸收,通过抑制 NF-κB p65 磷酸化水平,降解 IκBα 蛋白,以及降低 p65 的核转位起作用。

Rubiadin-1-methyl ether

Rubiadin-1-methyl ether Chemical Structure

CAS No. : 7460-43-7

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生物活性

Rubiadin-1-methyl ether is a natural anthraquinone isolated from Morinda officinalis How, and inhibits osteoclastic bone resorption via inhibition on the phosphorylation of NF-κB p65 and the degradation of IκBα as well as decrease in the nuclear translocation of p65[1].

IC50 & Target[1]

p65

 

分子量

268.26

Formula

C16H12O4

CAS 号

7460-43-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. He YQ, et al. Rubiadin-1-methyl ether from Morinda officinalis How. Inhibits osteoclastogenesis through blocking RANKL-induced NF-κB pathway. Biochem Biophys Res Commun. 2018 Dec 2;506(4):927-931.