标签归档：human

PD-1（人）ELISA试剂盒 PD-1 (human) ELISA Kit

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PD-1（人）ELISA试剂盒
PD-1 (human) ELISA Kit

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PD-1（人）ELISA试剂盒 PD-1 (human) ELISA Kit

PD-1 (human) ELISA Kit

PD-1 (人) ELISA试剂盒



◆规格/处理


产品细节

别名

　CD279；细胞程序性死亡蛋白1

产品规格

　套

性能

应用

　定量ELISA

特异性

　在血清，血浆和细胞培养上清液中检测可溶性的人PD-1（sPD-1）。

交叉反应

　人

数量

　1×96 wells

灵敏度

　1.6 pg/mL

检测范围

　3.125 ~200 pg/mL

样品类型

　细胞培养上清液、血浆、血清

分析类型

　夹心法

检测类型

　比色法

其他产品数据

　UniProt link Q15116:   PD-1 (human)

登记号

　Q15116

运输和处理

运输

　冰袋（BI）

短期储存

　+4°C

长期储存

　+4°C

建议保存方法

　●　标准品配制后，分装好并储存在-20°C。
　●　避免反复冻融。
　●　微孔板和试剂使用前应回温至室温。

使用/稳定性

　有效期为生产后的12个月。请参阅ELISA试剂盒上的失效日期。

◆描述


PD-1（也称为细胞程序性死亡蛋白1；CD279）是CD28/CTLA-4免疫受体家族的I型跨膜蛋白，参与信号和免疫调节。CD28/CTLA-4家族成员可以促进T细胞活性（CD28和ICOS），也可以下调T细胞活性（CTLA-4和PD-1）。PD-1在活化的T细胞、B细胞、骨髓细胞和胸腺细胞中均有表达。PD-1与PD-L1（B7-H1；CD274）或PD-L2（B7-DC；CD273）结合后，可抑制TCR介导的T细胞增殖和生成IL-1、IL-4、IL-10和IFN-γ。另外，PD-1结合后也抑制BCR介导的信号传导。PD-1缺陷型小鼠会有外周耐受性缺陷，会自发发展为自身免疫疾病。可溶性的PD-1（sPD-1）能在活化的免疫细胞中表达，并且可以在血清/血浆中分泌。sPD-1或sPD-L1等可溶性检查点，会参与到正负免疫调节，它们在血清、血浆水平的变化会影响癌症的发展、预测和治疗。不同癌症的患者，所检测到sPD-1或sPD-L1水平会有所升高。PD-1（人）ELISA试剂盒是为检测不同的生物体液中特异性sPD-1（人）而开发的。


PD-1（人）ELISA试剂盒 PD-1 (human) ELISA Kit

标准曲线



※ 本页面产品仅供研究用，研究以外不可使用。

产品列表
产品编号 产品名称 产品规格 产品等级 备注
AG-45B-0015-KI01  PD-1 (human) ELISA Kit
 PD-1 (人) ELISA试剂盒		 96 wells

Tim-4（小鼠）：Fc（人）（重组）（生物素标记） Tim-4 (mouse):Fc (human) (rec.) (Biotin)

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Tim-4（小鼠）：Fc（人）（重组）（生物素标记）
Tim-4 (mouse):Fc (human) (rec.) (Biotin)

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  • Q&A
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Tim-4（小鼠）：Fc（人）（重组）（生物素标记）

参考文献


[1]

A novel affinity-based method for the isolation of highly purified extracellular vesicles:W. Nakai, et al.; Sci. Rep. 6, 33935 (2016)

[2]

High purity isolation and sensitive quantification of extracellular vesicles using affinity to Tim-4: T. Yoshida, et al.; Curr. Prot. Cell Biol. 77, 3.45.1-3.45.18 (2017)

产品列表
产品编号 产品名称 产品规格 产品等级 备注
AG-40B-0180B-C010 Tim-4 (mouse):Fc (human) (rec.) (Biotin)
 Tim-4 (小鼠):Fc (人) (重组) (生物素标记)		 10 µg – –
AG-40B-0180B-3010 Tim-4 (mouse):Fc (human) (rec.) (Biotin)
 Tim-4 (小鼠):Fc (人) (重组) (生物素标记)		 3 x 10 µg – –

GIP, human TFA(Synonyms: 抑胃肽三氟乙酸盐 (人) Gastric Inhibitory Peptide (GIP), human TFA)

发表于由

GIP, human TFA (Synonyms: 抑胃肽三氟乙酸盐 (人); Gastric Inhibitory Peptide (GIP), human TFA) 纯度: 96.24%

GIP, human TFA 是一种由 42 个氨基酸组成的肽类激素，是葡萄糖依赖性胰岛素分泌的促进剂和胃酸分泌的弱抑制剂。GIP, human TFA 作为肠 K 细胞释放的肠促胰岛素激素，对营养摄入作出反应。

GIP, human TFA (Synonyms: 抑胃肽三氟乙酸盐 (人); Gastric Inhibitory Peptide (GIP), human TFA)

GIP, human TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ￥5000 In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

GIP, human TFA 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

GIP, human TFA, a peptide hormone consisting of 42 amino acids, is a stimulator of glucose-dependent insulin secretion and a weak inhibitor of gastric acid secretion. GIP, human TFA acts as an incretin hormone released from intestinal K cells in response to nutrient ingestion[1][2][3].

体外研究
(In Vitro)

Gastric Inhibitory Polypeptide (GIP) exerts various peripheral effects on adipose tissue and lipid metabolism, thereby leading to increased lipid deposition in the postprandial state[1]. GIP, human plays a vital role in lipid metabolism and the development of obesity.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

5097.62

Formula

C228H339F3N60O68S
Sequence

Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln
Sequence Shortening

YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
中文名称

抑胃肽三氟乙酸盐 (人)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Protect from light, stored under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13.

    [2]. Miyachi A, et al. Quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS. J Proteome Res. 2013;12(6):2690-2699.

    [3]. Gabe MBN, et al. Molecular interactions of full-length and truncated GIP peptides with the GIP receptor – A comprehensive review. Peptides. 2020;125:170224.

  • [1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13.

    [2]. Miyachi A, et al. Quantitative analytical method for determining the levels of gastric inhibitory polypeptides GIP1-42 and GIP3-42 in human plasma using LC-MS/MS/MS. J Proteome Res. 2013;12(6):2690-2699.

    [3]. Gabe MBN, et al. Molecular interactions of full-length and truncated GIP peptides with the GIP receptor – A comprehensive review. Peptides. 2020;125:170224.

PAMP-12(human, porcine)

发表于由

PAMP-12(human, porcine)  纯度: 99.03%

PAMP-12(human, porcine) 是免疫反应性 (ir)-PAMP 的一种主要成分，由肾上腺髓质素前体加工而成，是一种有效的降压肽，可参与心血管方面的调控。

PAMP-12(human, porcine)&nbsp;

PAMP-12(human, porcine) Chemical Structure

CAS No. : 196305-05-2

规格 价格 是否有货 数量
1 mg ￥1200 In-stock
5 mg ￥3600 In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

PAMP-12(human, porcine) 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control[1].

体外研究
(In Vitro)

PAMP-12 (human, porcine) is the PAMP[9-20] with a C-terminal amide structure. Intravenous injections of PAMP-12 in anesthetized rats show a significant hypotensive effect in a dose-dependent fashion[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1618.93

Formula

C77H119N25O14
CAS 号

196305-05-2
Sequence Shortening

FRKKWNKWALSR-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -80°C 2 years
-20°C 1 year
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献

  • [1]. K Kuwasako, et al. Purification and Characterization of PAMP-12 (PAMP[9-20]) in Porcine Adrenal Medulla as a Major Endogenous Biologically Active Peptide. FEBS Lett. 1997 Sep 1;414(1):105-10.

  • [1]. K Kuwasako, et al. Purification and Characterization of PAMP-12 (PAMP[9-20]) in Porcine Adrenal Medulla as a Major Endogenous Biologically Active Peptide. FEBS Lett. 1997 Sep 1;414(1):105-10.

新抗体！Anti-Human LAT1-CD98, CD4, CD8

发表于由

新抗体！Anti-Human LAT1-CD98, CD4, CD8

 

1）Anti Human LAT1-CD98 Rat IgG Monoclonal (#CAC-LKG-M004 and LKG-M005)

  CosmoBio成功研发出了用于检测天然LAT1胞外膜区域的CD98C5复合物的高亲和力抗体。

  LAT1（L-型氨基酸转运蛋白1）是一个具有12个跨膜结构域的氨基酸转运蛋白。它可以作为二硫键连接的异源二聚体与CD98重链（CD98hc）结合。这种结合了CD98hc和LAT1（CD98C5）的异源二聚体，通过质膜1.2）转运大量中性氨基酸（亮氨酸，异亮氨酸，缬氨酸，苯丙氨酸，酪氨酸，色氨酸，蛋氨酸和组氨酸）。已知CD98C5复合物在各种癌症患者身上频繁且特异性过度表达，成为了新一代作为人类癌症治疗3-6）的候选分子靶标。以前由于它的氨基酸数量小于30个，使抗体难以识别LAT1的细胞外结构域，但现在CosmoBioAnti LAT1-CD98 antibody（CAC-LKGM005）帮您完美的解决了这个问题。

 

抗原/来源：LAT1-CD98复合物

宿主：大鼠

交叉反应：人

克隆号：RH01

类型：IgG2a

共轭结合：未标记

片段：免疫球蛋白部分 – 蛋白质G

应用范围：免疫荧光/流式细胞仪


 


2）Anti CD4 antibody (#CAC-NIH-NA-01)


M-GGMC-1是识别外周α链的-小鼠单克隆抗体。

 

抗原/来源：CD4

宿主：大鼠

交叉反应：金鱼/鲤鱼/斑马鱼

克隆号：6D1

应用范围：流式细胞仪


 

 

3）Anti CD8(α) antibody (#CAC-NIH-NA-02)


抗原/来源：CD8

宿主：大鼠

交叉反应：金鱼/鲤鱼/斑马鱼

克隆号：2C3

应用范围：流式细胞仪/免疫组化


  

4） Anti BP180/type XVII collagen antibody, Human (#CAC-NU-01-BP2)


抗原/来源：BP180抗原/ / XVII型胶原

宿主：老鼠

交叉反应：人

克隆号：4

应用范围：免疫印迹，免疫沉淀，免疫荧光

 新抗体！Anti-Human LAT1-CD98, CD4, CD8新抗体！Anti-Human LAT1-CD98, CD4, CD8

 


5）Anti keratin 8 chain antibody (#CAC-NU-01-KE8)

 

抗原/来源：角蛋白8链

宿主：小鼠

交叉反应：人/兔

克隆号：RL273

应用范围：Western印迹/免疫

新抗体！Anti-Human LAT1-CD98, CD4, CD8新抗体！Anti-Human LAT1-CD98, CD4, CD8

 


6） Anti laminin (γ)2 chain antibody (#CAC-NU-01-LA2)


抗原/来源：层粘连蛋白γ2链

宿主：小鼠

交叉反应：人/牛

克隆号：：YN557

应用范围：Western印迹/免疫/免疫沉淀


 


7）Anti Dock3 antibody, Mouse (#COP-COP-080064)


抗原/来源：Dock3

宿主：兔子

免疫原：小鼠

片段：亲和纯化

应用范围：Western印迹/免疫组化


 

FGF-basic 154 (human), (recombinant) 成纤维细胞生长因子碱性154（人），（重组） 品牌：Enzo

发表于由

FGF-basic 154 (human), (recombinant)

成纤维细胞生长因子碱性154（人），（重组）

品牌：Enzo
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

ALX-201-823-0100

 – 100 µg – 10,980.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Nordic-MUbio X1635C Human Placenta Tissue 100 µg

发表于由

上海金畔生物科技有限公司提供Nordic-MUbio X1635C Human Placenta Tissue 100 µg，欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

Nordic-MUbio X1635C Human Placenta Tissue 100 µg 2835.00

Nordic-MUbio X1634C Human Heart Tissue 100 µg 2835.00

Nordic-MUbio X1633C Human Brain Tissue 100 µg 2835.00

Nordic-MUbio X1632B Sphingosine Kinase 1 Blocking Peptide 50 µg 1995.00

Nordic-MUbio X1631P Rabbit anti Human Sphingosine 1-Phosphate Lyase 1 100 µg 5943.00

Nordic-MUbio X1630M Mouse anti Rat Adrenergic Receptor 100 µg 5943.00

Nordic-MUbio X1628P Rabbit anti Human Sphingosine Kinase 2 100 µg 4179.00

Nordic-MUbio X1627P Rabbit anti Human Sphingosine Kinase 1 100 µg 5943.00

Nordic-MUbio X1626M Mouse anti Human Sphingosine 1 Phosphate 4 Receptor (CT) (EDG6), conjugated with FITC 100 µg 7371.00

Nordic-MUbio X1623K2 BrdU Chemiluminescent Cell Proliferation Assay Kit 1000 Tests 9324.00

Nordic-MUbio X1623K1 BrdU Chemiluminescent Cell Proliferation Assay Kit 200 Tests 4767.00

Nordic-MUbio X1610M Mouse anti Gram Negative Bacteria DNA Adenine Methylase 100 µg 4179.00

Nordic-MUbio X1603M Mouse anti Human Muc1 100 µg 4179.00

Nordic-MUbio X1602M Mouse anti Human Muc1 100 µg 4179.00

Nordic-MUbio X1600P Rabbit anti Human OGR1/GPR68 100 µg 7371.00

Nordic-MUbio X1598M Mouse anti Rat SNAP25 100 µg 4179.00

Nordic-MUbio X1597M Mouse anti Rat SNAP25 100 µg 4179.00

Nordic-MUbio X1596P Rabbit anti Rat BAG-5 100 µg 4179.00

Nordic-MUbio X1595P Rabbit anti Human Gi alpha 1/2 100 µg 4179.00

Nordic-MUbio X1594P Rabbit anti Rat G Protein b5-D1 100 µg 4179.00

Ribonuclease Inhibitor, Human Placenta, recombinant, Solution 核糖核酸酶抑制剂 品牌：FUJIFILM Wako

发表于由

Ribonuclease Inhibitor, Human Placenta, recombinant, Solution

核糖核酸酶抑制剂

品牌：FUJIFILM Wako
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

181-01821

 for Genetic Research 5000units – 2,470.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Ribonuclease Inhibitor, Human Placenta, recombinant, Solution 核糖核酸酶抑制剂 品牌：FUJIFILM Wako

发表于由

Ribonuclease Inhibitor, Human Placenta, recombinant, Solution

核糖核酸酶抑制剂

品牌：FUJIFILM Wako
CAS No.：
储存条件：-20℃
纯度：–
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

187-01823

 for Genetic Research 25000Units – 11,560.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

Nordic-MUbio CD5-2-1 CD5, human 1 ml

发表于由

上海金畔生物科技有限公司提供Nordic-MUbio CD5-2-1 CD5, human 1 ml，欢迎访问官网了解更多产品信息和订购

品牌 货号 产品名称 规格 价格

Nordic-MUbio CD5-2-1 CD5, human 1 ml 9240.00

Nordic-MUbio CD34-1 CD34, human 1 ml 6405.00

Nordic-MUbio CD1A-O10 CD1a, human (O10) 1 ml 7665.00

Nordic-MUbio CD1A-MTB CD1a, human (MTB1) 1 ml 12495.00

Nordic-MUbio CD15-1 CD15, human 1 ml 5502.00

Nordic-MUbio CA199-1 CA 19-9, Sialyl-Lewis a 1 ml 8127.00

Nordic-MUbio CA102 Calcitonin 1 ml 9870.00

Nordic-MUbio C3C001-F Complement Factor C3c : FITC 1 ml 7665.00

Nordic-MUbio BOR001 Borrelia 200 µg 7665.00

Nordic-MUbio BAS001-G Basal Cell Marker Cocktail 1, p63 Protein + HMW Cytokeratin 5 ml 4620.00

Nordic-MUbio AR105 Androgen Receptor 1 ml 7875.00

Nordic-MUbio AGE102-1.0 AGE, Advanced Glycation End Products 1 ml 15330.00

Nordic-MUbio AE002 Peroxidase Substrate Kit AEC, 2 Components 1000 Tests 1764.00

Nordic-MUbio AA505 Alpha-Actin, sarcomeric 5 ml 3318.00

Nordic-MUbio CK514 Cytokeratin 14 5 ml 3318.00

Nordic-MUbio CK507 Cytokeratin 7 5 ml 3948.00

Nordic-MUbio CA130 Calretinin, monoclonal 1 ml 5922.00

Nordic-MUbio CA120-0.5 Calretinin 0.5 ml 3318.00

Nordic-MUbio Bii-rGFP-100 Purified recombinant Green Fluorescent Protein (wild type) 0.1mg 4767.00

Nordic-MUbio Bii-nGFPabC1-100 Chicken anti-native Green Fluorescent Protein 0.1ml 4200.00