标签归档：cis

cis-Scirpusin B 品牌：Nagara Science

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cis-Scirpusin B

品牌：Nagara Science
CAS No.：
储存条件：-20℃,Dark Strage
纯度：≧99% (HPLC)
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

NS301001

 – 2 mg – 咨询 – –


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4-O-beta-Glucopyranosyl-cis-coumaric acid(Synonyms: 香豆酸-4-葡萄糖苷)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

4-O-beta-Glucopyranosyl-cis-coumaric acid;(Synonyms: 香豆酸-4-葡萄糖苷)

4-O-beta-Glucopyranosyl-cis-coumaric acid 是从Nelumbo nucifera Gaertn 中提取得到的一种天然产物。

4-O-beta-Glucopyranosyl-cis-coumaric acid(Synonyms: 香豆酸-4-葡萄糖苷)

4-O-beta-Glucopyranosyl-cis-coumaric acid Chemical Structure

CAS No. : 117405-48-8

规格 价格 是否有货
1 mg ￥5140 询问价格 货期
5 mg ￥15430 询问价格 货期

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生物活性

4-O-beta-Glucopyranosyl-cis-coumaric acid is a natural compound isolated formn Nelumbo nucifera Gaertn.

分子量

326.30

Formula

C15H18O8
CAS 号

117405-48-8
中文名称

香豆酸-4-葡萄糖苷
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

3-cis-Hydroxyglibenclamide 1,3-双羟基格列本脲 品牌：Chemodex

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3-cis-Hydroxyglibenclamide

1,3-双羟基格列本脲

品牌：Chemodex
CAS No.：23074-02-4
储存条件：-20°C
纯度：>97% (HPLC)
产品编号

(生产商编号)

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CDX-H0030-M001

 – 1 mg – 2,040.00 – –


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3-cis-Hydroxyglibenclamide 1,3-双羟基格列本脲 品牌：Chemodex

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3-cis-Hydroxyglibenclamide

1,3-双羟基格列本脲

品牌：Chemodex
CAS No.：23074-02-4
储存条件：-20°C
纯度：>97% (HPLC)
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

CDX-H0030-M005

 – 5 mg – 8,160.00 – –


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cis-Mulberroside A(Synonyms: Mulberroside D)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

cis-Mulberroside A;(Synonyms: Mulberroside D)

cis-Mulberroside A (Mulberroside D) 是 Mulberroside A 的顺式异构体。Mulberroside A 是桑树 (Morus alba L.) 中的主要生物活性成分之一。Mulberroside A 可降低 TNF-α，IL-1β 和 IL-6 的表达，抑制 NALP3，caspase-1 和 NF-κB 的激活以及 ERK，JNK 和 p38 的磷酸化 。Mulberroside A 具有抗炎和抗细胞凋亡作用。Mulberroside A 对蘑菇酪氨酸酶 ( tyrosinase) 具有抑制活性，IC50 为 53.6 μM。

cis-Mulberroside A(Synonyms: Mulberroside D)

cis-Mulberroside A Chemical Structure

CAS No. : 166734-06-1

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生物活性

cis-Mulberroside A (Mulberroside D) is the cis-isomer of Mulberroside A. Mulberroside A is one of the main bioactive constituent in mulberry (Morus alba L.)[1]. Mulberroside A decreases the expressions of TNF-α, IL-1β, and IL-6 and inhibits the activation of NALP3, caspase-1, and NF-κB and the phosphorylation of ERK, JNK, and p38, exhibiting anti-inflammatory and anti-apoptotic effects[2]. Mulberroside A shows inhibitory activity against mushroom tyrosinase with an IC50 of 53.6 μM[3].

体内研究
(In Vivo)

Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic mice[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Kun-Ming mice (20±2 g)[4]
Dosage: 5, 10, 20, and 40 mg/kg; the dose volume 10 mL/kg body weight
Administration: Orally initiated at 9:00 a.m.
Result: 10, 20, and 40 mg/kg significantly increased urinary urate excretion in 24 h, resulting in a remarkable elevation of fractional excretion of uric acid (FEUA), and the highest dose completely reversed FEUA alteration of hyperuricemic mice to normal.

分子量

568.52

Formula

C26H32O14
CAS 号

166734-06-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Mei M, et al. In vitro pharmacokinetic characterization of mulberroside A, the main polyhydroxylated stilbene in mulberry (Morus alba L.), and its bacterial metabolite oxyresveratrol in traditional oral use. J Agric Food Chem. 2012 Mar 7;60(9):2299-308.

    [2]. Wang CP, et al. Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion. J Neurosci Res. 2014 Jul;92(7):944-54.

    [3]. Kim JK, et al. Biotransformation of mulberroside A from Morus alba results in enhancement of tyrosinase inhibition. J Ind Microbiol Biotechnol. 2010 Jun;37(6):631-7.

    [4]. Cai-Ping Wang,et al. Mulberroside a possesses potent uricosuric and nephroprotective effects in hyperuricemic mice. Planta Med. 2011 May;77(8):786-94.

cis-Tiliroside(Synonyms: 顺式银椴苷)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

cis-Tiliroside;(Synonyms: 顺式银椴苷)

cis-Tiliroside 是一种山奈酚衍生物，是一种黄酮苷。cis-Tiliroside在 A549 细胞系中表现出比 trans-Tiliroside 更好的细胞毒性。

cis-Tiliroside(Synonyms: 顺式银椴苷)

cis-Tiliroside Chemical Structure

CAS No. : 163956-16-9

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生物活性

cis-Tiliroside, a kaempferol derivative, is a flavonoid glycoside. cis-Tiliroside exhibits better cytotoxic activity than trans-Tiliroside in A549 cell line[1].

体外研究
(In Vitro)

cis-Tiliroside has CC50s of 68.05 μg/mL and 18.82 μg/mL for A549 cell line in 24 h or 48 h, respectively. trans-Tiliroside has CC50s of 149.90 μg/mL and 144.74 μg/mL for A549 cell line in 24 h or 48 h, respectively[1].
cis-Tiliroside exhibits better cytotoxic activity than kaempferol, which has CC50s of 129.15 μg/mL and 113.48 μg/mL for A549 cell line in 24 h or 48 h, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

594.52

Formula

C30H26O13
CAS 号

163956-16-9
中文名称

顺式银椴苷
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Chi-Ren Liao, et al. Studies on cytotoxic constituents from the leaves of Elaeagnus oldhamii Maxim. in non-small cell lung cancer A549 cells. Molecules. 2014 Jul 4;19(7):9515-34.

Decahydronaphthalene (mixture of cis- and trans-) 品牌：FUJIFILM Wako

发表于由

Decahydronaphthalene (mixture of cis- and trans-)

品牌：FUJIFILM Wako
CAS No.：91-17-8
储存条件：室温
纯度：97.0+% (cGC)(mixture of isomers)
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

040-16491

 for Electrophoresis 3L – 咨询 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

9-cis-Retinal(Synonyms: 9-顺式视黄醛)

发表于由

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

9-cis-Retinal (Synonyms: 9-顺式视黄醛) 纯度: ≥98.0%

9-cis-Retinal 是天然的类视黄醇。饮食中的 99-cis-β-carotene 通过裂解成 9-cis-retinoids 生成 9-cis-Retinal。9-cis-Retinal 与细胞视黄醇结合蛋白-I (CRBP-1) 和 CRBP-II 的 Kd 分别为 8 nM 和 5 nM。9-cis-Retinal 加快了视网膜类器官中杆感光细胞的分化和成熟。

9-cis-Retinal(Synonyms: 9-顺式视黄醛)

9-cis-Retinal Chemical Structure

CAS No. : 514-85-2

规格 价格 是否有货 数量
1 mg ￥2300 In-stock
5 mg   询价  
10 mg   询价  

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生物活性

9-cis-Retinal is a natural retinoid. Dietary 9-cis-β-carotene generates 9-cis-retinoids via cleavage into 9-cis-retinal. 9-cis Retinal binds to cellular retinol-binding protein-I (CRBP-I) and CRBP-II with Kds of 8 nM and 5 nM, respectively. 9-cis-Retinal expedites differentiation and maturation of rod photoreceptors in retinal organoids[1][2][3].

IC50 & Target[1][2]

Human Endogenous Metabolite

 

体外研究
(In Vitro)

The addition of 9-cis-Retinal, instead of the widely used all-trans retinoic acid, accelerates rod photoreceptor differentiation in organoid cultures, with higher rhodopsin expression and more mature mitochondrial morphology evident by day. 9-cis-Retinal can bind opsin to form functioning rhodopsin[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

Treatment with 9-cis-retinal produced a significant recovery of the cone response in interphotoreceptor retinoid-binding protein (IRBP)-/- mice and shows that retinoid deficiency underlies cone dysfunction[4].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

284.44

Formula

C20H28O
CAS 号

514-85-2
中文名称

9-顺式视黄醛
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
参考文献

  • [1]. Kane MA, et al. Binding affinities of CRBPI and CRBPII for 9-cis-retinoids.Biochim Biophys Acta. 2011 May;1810(5):514-8.

    [2]. Mertz JR, et al. Identification and characterization of a stereospecific human enzyme that catalyzes 9-cis-retinol oxidation. A possible role in 9-cis-retinoic acid formation. J Biol Chem. 1997 May 2;272(18):11744-9.

    [3]. Kaya KD, et al. Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal. Mol Vis. 2019 Nov 11;25:663-678.

    [4]. Parker RO, et al. Normal cone function requires the interphotoreceptor retinoid binding protein. J Neurosci. 2009 Apr 8;29(14):4616-21.

cis-Isolimonenol(Synonyms: (1S,4R)-p-Mentha-2,8-dien-1-ol)

发表于由

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

cis-Isolimonenol (Synonyms: (1S,4R)-p-Mentha-2,8-dien-1-ol) 纯度: 98.92%

cis-Isolimonenol ((1S,4R)-p-Mentha-2,8-dien-1-ol) 是精油的一种化学组成成分。

cis-Isolimonenol(Synonyms: (1S,4R)-p-Mentha-2,8-dien-1-ol)

cis-Isolimonenol Chemical Structure

CAS No. : 22972-51-6

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg)   Apply now  
10 mM * 1 mL in DMSO ￥550 In-stock
500 mg ￥500 In-stock
1 g   询价  
5 g   询价  

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cis-Isolimonenol 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Fragment Library
  • Medicine Food Homology Compound Library
  • Terpenoids Library
  • Food-Sourced Compound Library

生物活性

cis-Isolimonenol ((1S,4R)-p-Mentha-2,8-dien-1-ol) is a chemical composition of essential oil[1].

分子量

152.23

Formula

C10H16O
CAS 号

22972-51-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 100 mg/mL (656.90 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 6.5690 mL 32.8450 mL 65.6901 mL
5 mM 1.3138 mL 6.5690 mL 13.1380 mL
10 mM 0.6569 mL 3.2845 mL 6.5690 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂： 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (16.42 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (16.42 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂： 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (16.42 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (16.42 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂： 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (16.42 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (16.42 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
参考文献

  • [1]. Vinutha M, et al. EFFECT OF DIFFERENT ABIOTIC STRESS ON ESSENTIAL OIL YIELD FROM AERIAL PART OF CYMBOPOGON FLEXUOSUS (NEES EX STEUD) WATS. Int J Approx Reason1.982. 2016 Dec;4(12):1490-1504.