天然产物 糖类和糖苷 Saccharides and Glycosides
Pseudoginsenoside F11;(Synonyms: 拟人参皂苷 F11; Ginsenoside A1) 纯度: ge;98.0%
Pseudoginsenoside F11 (Ginsenoside A1) 是西洋参的组成成分,能够抵抗小鼠由莨菪碱、吗啡、脱氧麻黄碱诱导的学习记忆能力缺失。
Pseudoginsenoside F11 Chemical Structure
CAS No. : 69884-00-0
规格 | 价格 | 是否有货 | 数量 |
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10;mM;*;1 mL in DMSO | ¥775 | In-stock | |
5 mg | ¥600 | In-stock | |
10 mg | ¥880 | In-stock | |
50 mg | ; | 询价 | ; |
100 mg | ; | 询价 | ; |
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Pseudoginsenoside F11 相关产品
bull;相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
- Metabolism/Protease Compound Library
- Natural Product Library
- Human Endogenous Metabolite Compound Library
- Glycoside Compound Library
- Medicine Food Homology Compound Library
- Terpenoids Library
- Traditional Chinese Medicine Monomer Library
- Food-Sourced Compound Library
生物活性 |
Pseudoginsenoside F11 (Ginsenoside A1), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice. |
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IC50 Target |
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体外研究 (In Vitro) |
Biochemical experiments revealed that Pseudoginsenoside F11 (Ginsenoside A1) could inhibit diprenorphine (DIP) binding with an IC50 of 6.1 μM and reduced the binding potency of morphine in Chinese hamster ovary (CHO)-μ cells[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
One in vivo model of cisplatin-induced acute renal failure was performed. The results showed that pretreatment with Pseudoginsenoside Pseudoginsenoside F11 (Ginsenoside A1) reduced cisplatin-elevated blood urea nitrogen and creatinine levels, as well as ameliorated the histophathological damage [1]. We tested the effects of Pseudoginsenoside Pseudoginsenoside F11 (Ginsenoside A1) on morphine-induced development of behavioral sensitization and alterations in glutamate levels in the medial prefrontal cortex (mPFC) in freely moving mice by using in vivo microdialysis. As the results shown, Pseudoginsenoside Pseudoginsenoside F11 (Ginsenoside A1) antagonized the development of behavioral sensitization and decrease of glutamate in the mPFC induced by morphine[3]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
801.01 |
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Formula |
C42H72O14 |
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CAS 号 |
69884-00-0 |
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中文名称 |
拟人参皂苷 F11;伪人参皂苷 F11 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4deg;C, sealed storage, away from moisture and light *In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light) |
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溶解性数据 |
In Vitro:;
DMSO : 100 mg/mL (124.84 mM; Need ultrasonic) H2O : 0.67 mg/mL (0.84 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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