上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。
Ferulenol
Ferulenol，倍半萜烯丙基香豆素衍生物，在泛醌循环水平上特异性抑制琥珀酸泛醌还原酶。 Ferulenol 具有良好的抗分枝杆菌活性和止血作用。
Ferulenol Chemical Structure
CAS No. : 6805-34-1
| 规格 | 是否有货 | ||
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| 1 mg | 询价 | ||
| 5 mg | 询价 | ||
| 10 mg | 询价 |
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| 生物活性 |
Ferulenol, a sesquiterpene prenylated coumarin derivative, specifically inhibits succinate ubiquinone reductase at the level of the ubiquinonecycle. Ferulenol shows good antimycobacterial activity and haemorrhagic action[1][2][3]. |
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| 体外研究 (In Vitro) |
Ferulenol inhibits the oxidative phosphorylation process by interacting with adenine nucleotide translocase (ANT) and the complex II of the respiratory chain. At low concentrations, ferulenol inhibited ATP synthesis by inhibition of the adenine nucleotide translocase without limitation of mitochondrial respiration. At higher concentrations, ferulenol inhibited oxygen consumption. Ferulenol caused specific inhibition of succinate ubiquinone reductase without altering succinate dehydrogenase activity of the complex II[1]. Ferulenol inhibits succinate ubiquinone reductase(SQR) activity in a concentration-dependent manner and is as effective as thenoyltrifluoroacetone (TTFA)[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
366.49 |
| Formula |
C24H30O3 |
| CAS 号 |
6805-34-1 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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