Tirzepatide;(Synonyms: LY3298176)
Tirzepatide (LY3298176) 是葡萄糖依赖性胰岛素营养多肽 (GIP) 和胰高血糖素样肽-1 (GLP-1) 受体双重激动剂,有潜力用于 2 型糖尿病的研究。
Tirzepatide Chemical Structure
CAS No. : 2023788-19-2
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是否有货 |
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100 mg |
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250 mg |
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500 mg |
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Tirzepatide 的其他形式现货产品:
Tirzepatide hydrochloride
生物活性 |
Tirzepatide (LY3298176) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that is being developed for the treatment of type 2 diabetes[1].
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体内研究 (In Vivo) |
Tirzepatide (LY3298176) shows significantly better efficacy with regard to glucose control and weight loss than do Dulaglutide[1].
MCE has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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Formula |
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Sequence Shortening |
Y-{Aib}-EGTFTSDYSI-{Aib}-LDKIAQ-{diacid-gamma-Glu-(AEEA)2-Lys}-AFVQWLIAGGPSSGAPPPS-NH2
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运输条件 |
Room temperature in continental US; may vary elsewhere.
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献 |
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[1]. Frias JP, et al. Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial. Lancet. 2018 Nov 17;392(10160):2180-2193.
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