标签归档：rc

RIBI-529(Synonyms: RC-529)

发表于由

生化分析试剂 Biochemical Assay Reagents
RIBI-529;(Synonyms: RC-529)

RIBI-529 (RC-529) 是一种脂质 A 模拟物 (氨基烷基氨基葡糖 4-磷酸盐)，是一种与 MPL (Corixa) 功效相似的佐剂。RIBI-529 通过 Toll 样受体 4 发出信号以刺激先天免疫系统。

RIBI-529(Synonyms: RC-529)

RIBI-529 Chemical Structure

CAS No. : 216014-46-9

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

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生物活性

RIBI-529 (RC-529), a lipid A mimetic (aminoalkyl glucosaminide 4-phosphate), is a adjuvant with a similar efficacy to MPL (Corixa). RIBI-529 signals through Toll-like receptor 4 to stimulate the innate immune system[1].

分子量

1713.54

Formula

C98H190N3O17P
CAS 号

216014-46-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jay T Evans, et al. Enhancement of antigen-specific immunity via the TLR4 ligands MPL adjuvant and Ribi.529. Expert Rev Vaccines. 2003 Apr;2(2):219-29.

Ginsenoside Rc(Synonyms: 人参皂苷 Rc; Panaxoside Rc)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

Ginsenoside Rc;(Synonyms: 人参皂苷 Rc; Panaxoside Rc) 纯度: ge;98.0%

Ginsenoside Rc 是主要的人参皂甙之一，Ginsenoside Rc 增强 GABA 受体 A (GABAA) 介导的离子通道 (IGABA)电流。 Ginsenoside Rc 还抑制 TNF-α 和 IL-1β 表达。

Ginsenoside Rc(Synonyms: 人参皂苷 Rc; Panaxoside Rc)

Ginsenoside Rc Chemical Structure

CAS No. : 11021-14-0

规格 价格 是否有货 数量
10;mM;*;1 mL in Water ￥1425 In-stock
5 mg ￥700 In-stock
10 mg ￥1200 In-stock
50 mg ; 询价 ;
100 mg ; 询价 ;

* Please select Quantity before adding items.

Ginsenoside Rc 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Apoptosis Compound Library
  • Immunology/Inflammation Compound Library
  • Membrane Transporter/Ion Channel Compound Library
  • Neuronal Signaling Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Differentiation Inducing Compound Library
  • Glycoside Compound Library
  • Medicine Food Homology Compound Library
  • Terpenoids Library
  • Pyroptosis Compound Library
  • Neurotransmitter Receptor Compound Library
  • Traditional Chinese Medicine Monomer Library
  • Anti-Alzheimer’s Disease Compound Library
  • Neuroprotective Compound Library
  • Anti-Parkinson’s Disease Compound Library
  • Neurodegenerative Disease-related Compound Library
  • Angiogenesis Related Compound Library
  • Food-Sourced Compound Library

生物活性

Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances GABA receptorA (GABAA)-mediated ion channel currents (IGABA). Ginsenoside Rc inhibits the expression of TNF-α and IL-1β.

IC50 Target[2]

TNF-α

;

IL-1β

;

体外研究
(In Vitro)

Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances γ-aminobutyric acid (GABA) receptorA (GABAA)-mediated ion channel currents. Ginsenoside Rc enhances GABA-mediated ion currents in oocytes expressing the GABAA receptor[1]. Ginsenoside Rc significantly inhibits the expression of macrophage-derived cytokines, such as TNF-α and IL-1β. Ginsenoside Rc also markedly suppresses the activation of TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling in activated RAW264.7 macrophages, human synovial cells, and HEK293 cells. Ginsenoside Rc exerts its anti-inflammatory actions by suppressing TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling. Ginsenoside Rc suppresses the nuclear translocation of phospho-ATF-2 and phospho-FRA-1, whereas the translocation of p65 at its peak time points (30 and 60 min) is not decreased by Ginsenoside Rc treatment. Ginsenoside Rc regulates the expression of the proinflammatory cytokine TNF-α, which is produced by macrophages, by suppressing AP-1 activation[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1079.27

Formula

C53H90O22
CAS 号

11021-14-0
中文名称

人参皂苷 Rc
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20deg;C 3 years
4deg;C 2 years
In solvent -80deg;C 6 months
-20deg;C 1 month
溶解性数据
In Vitro:;

H2O : 50 mg/mL (46.33 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.9266 mL 4.6328 mL 9.2655 mL
5 mM 0.1853 mL 0.9266 mL 1.8531 mL
10 mM 0.0927 mL 0.4633 mL 0.9266 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Lee BH, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60.

    [2]. Yu T, et al. Ginsenoside Rc from Panax ginseng exerts anti-inflammatory activity by targeting TANK-bindingkinase 1/interferon regulatory factor-3 and p38/ATF-2. J Ginseng Res. 2017 Apr;41(2):127-133.
Kinase Assay
[2]

To evaluate the effects of Ginsenoside Rc on kinase activity, immunoprecipitated TBK1, IKKε, and p38 are incubated in reaction buffer in the presence or absence of Ginsenoside Rc. The reactions are initiated by the addition of Mg-ATP. After a 30 min incubation at 30°C, the reactions are stopped by the addition of sample buffer and the samples are boiled. Kinase activity is assessed by immunoblotting with antibodies against the phospho-forms of IKKε, IRF-3, and ATF-2[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

  • [1]. Lee BH, et al. Effects of Ginsenoside Metabolites on GABAA Receptor-Mediated Ion Currents. J Ginseng Res. 2012 Jan;36(1):55-60.

    [2]. Yu T, et al. Ginsenoside Rc from Panax ginseng exerts anti-inflammatory activity by targeting TANK-bindingkinase 1/interferon regulatory factor-3 and p38/ATF-2. J Ginseng Res. 2017 Apr;41(2):127-133.

Malonylginsenoside Rc

发表于由

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Malonylginsenoside Rc 

Malonylginsenoside Rc 是一种具有抗增殖活性的天然活性化合物。

Malonylginsenoside Rc

Malonylginsenoside Rc Chemical Structure

CAS No. : 88140-36-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Malonylginsenoside Rc is a natural active compound with anti-proliferative activity[1].

体外研究
(In Vitro)

Malonylginsenoside Rc inhibits the growth of SH-SY5Y human neuroblastoma cell line with an IC50 of 63.27 μM[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1165.31

Formula

C56H92O25
CAS 号

88140-36-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zheng-Yi Qu, et al. New malonylginsenosides from the fresh fruits of Panax notoginseng. Fitoterapia. 2021 Apr;150:104844.

INFORSRC-306和RC-406落地式摇床

发表于由
INFORSRC-306和RC-406落地式摇床

INFORS RC－306和RC－406落地式摇床

产品编号：
市场价：￥0.00元
会员价：￥0.00元
品牌：INFORS
生产厂家：INFORS

  • 产品概览
  • 技术参数
  • 订购信息
  • 相关资料
  • 相关产品

主要特点：

其独特的设计，使其不用将摇床固定在地面，移动更方便。

技术参数：

 

型号

RC-406

振荡方式

回转式，振幅: ф50mm(ф75, 100mm可选)

振荡速度

20－400 rpm, 速度控制精度: ±1%

托盘尺寸

8个800×660（mm）

容量/托盘

96个2L摇瓶; 16个6L摇瓶

外形尺寸 / 重量

1590×916×1355（mm）/ 约470Kg

选型指南

30676: RC-406主机(振幅: ф50mm)

31223: C型，800 x 660 mm,通用振荡托板

31224: C型，800 x 660 mm,粘性振荡托板

不绣钢锥形瓶夹(25mL—2L)

塑料锥形瓶夹(100mL, 250mL, 500mL)

不绣钢Fernbach瓶夹(1.8L, 2.8L)

试管架(长度; 188mm)

塑料试管架(Ø 16 mm (15 ml); Ø 30 mm (50 ml))

63240: 粘性贴条, 200 x 200mm

 

 

whatman0.2 μm13针头式滤器，RC无菌

发表于由

简要描述：whatman Puradisc FP 0.2 μm13针头式滤器，RC无菌10462940
Puradisc 13mm针头式滤器结合了高质量和经济性。非常适合快速、高效过滤样品，大过滤量为10ml。

Ÿ标准进口和出口接头
Ÿ无菌包装和医疗级别包装
Ÿ多种材质滤膜
Puradisc™针头式滤器具有的质量，是较经济的选择。它可以快速有效的过滤样品，大过滤量为100 ml。

Puradi

产品型号： 10462940

所属分类：玻璃纤维滤膜

详情介绍

whatman Puradisc FP  0.2 μm13针头式滤器，RC无菌10462940

Puradisc 13mm针头式滤器结合了高质量和经济性。非常适合快速、高效过滤样品，大过滤量为10ml。

  • Ÿ标准进口和出口接头
  • Ÿ无菌包装和医疗级别包装
  • Ÿ多种材质滤膜

Puradisc™针头式滤器具有的质量，是经济的选择。它可以快速有效的过滤样品，过滤量为100 ml。

Puradisc滤器由无色聚丙烯或聚碳酸酯材料制成，有标准进口和出口接头(除非另有说明)。有无菌包装、医疗级别包装可选，还有特殊管出口可用于高精确度样品分离回收入微型管，避免了空气阻塞作用。

whatman0.2 μm13针头式滤器，RC无菌

LPS from E. coli J5 (Rc) TLRpure Sterile Solution 脂多糖来源于大肠杆菌J5 （Rc）TLR纯净无菌溶液 品牌：Innaxon

发表于由

LPS from E. coli J5 (Rc) TLRpure Sterile Solution

脂多糖来源于大肠杆菌J5 （Rc）TLR纯净无菌溶液

品牌：Innaxon
CAS No.：
储存条件：+4°C
纯度：>99.9%. No detectable DNA, RNA and protein traces.
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

IAX-100-014-C500

 – 500 µg – 1,810.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

LPS from E. coli J5 (Rc) TLRpure Sterile Solution 脂多糖来源于大肠杆菌J5 （Rc）TLR纯净无菌溶液 品牌：Innaxon

发表于由

LPS from E. coli J5 (Rc) TLRpure Sterile Solution

脂多糖来源于大肠杆菌J5 （Rc）TLR纯净无菌溶液

品牌：Innaxon
CAS No.：
储存条件：+4°C
纯度：>99.9%. No detectable DNA, RNA and protein traces.
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

IAX-100-014-M001

 – 1 mg – 2,770.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution 脂多糖来源于明尼苏达沙门氏菌 R5 （Rc） TLR纯净无菌溶液 品牌：Innaxon

发表于由

LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution

脂多糖来源于明尼苏达沙门氏菌 R5 （Rc） TLR纯净无菌溶液

品牌：Innaxon
CAS No.：
储存条件：+4°C
纯度：>99.9%. No detectable DNA, RNA and protein traces.
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

IAX-100-017-C500

 – 500 µg – 1,810.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution 脂多糖来源于明尼苏达沙门氏菌 R5 （Rc） TLR纯净无菌溶液 品牌：Innaxon

发表于由

LPS from S. minnesota R5 (Rc) TLRpure Sterile Solution

脂多糖来源于明尼苏达沙门氏菌 R5 （Rc） TLR纯净无菌溶液

品牌：Innaxon
CAS No.：
储存条件：+4°C
纯度：>99.9%. No detectable DNA, RNA and protein traces.
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

IAX-100-017-M001

 – 1 mg – 2,770.00 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。

LPS from E. coli J5 (Rc) TLRpure Sterile Solution 脂多糖来源于大肠杆菌J5 （Rc）TLR纯净无菌溶液 品牌：Innaxon

发表于由

LPS from E. coli J5 (Rc) TLRpure Sterile Solution

脂多糖来源于大肠杆菌J5 （Rc）TLR纯净无菌溶液

品牌：Innaxon
CAS No.：
储存条件：+4℃
纯度：≥99.9%
产品编号

(生产商编号)

 等级 规格 运输包装 零售价(RMB) 库存情况 参考值

IAX-100-014-5001

 – 5×1 mg –

LPS from E. coli J5 (Rc) TLRpure Sterile Solution 脂多糖来源于大肠杆菌J5 （Rc）TLR纯净无菌溶液 品牌：Innaxon

 – –


* 干冰运输、大包装及大批量的产品需酌情添加运输费用


* 零售价、促销产品折扣、运输费用、库存情况、产品及包装规格可能因各种原因有所变动，恕不另行通知，确切详情请联系上海金畔生物科技有限公司。