标签归档：amino

2-Amino-2-deoxyglucose hydrochloride

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

2-Amino-2-deoxyglucose hydrochloride; 纯度: ge;98.0%

2-Amino-2-deoxyglucose hydrochloride 是一种盐酸己糖胺，可用于合成环丙烯修饰的己糖胺衍生物 Ac4GlcNCyoc 和 Ac4GalNCyoc。

2-Amino-2-deoxyglucose hydrochloride

2-Amino-2-deoxyglucose hydrochloride Chemical Structure

CAS No. : 1078691-95-8

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
100 mg ￥350 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

2-Amino-2-deoxyglucose hydrochloride 相关产品

bull;相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Natural Product Library
  • Microbial Metabolite Library

生物活性

2-Amino-2-deoxyglucose hydrochloride is a hexosamine hydrochloride can be used in the synthesis of cyclopropene-modified hexosamine derivative Ac4GlcNCyoc and Ac4GalNCyoc[1].

分子量

215.63

Formula

C6H14ClNO5
CAS 号

1078691-95-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, sealed storage, away from moisture

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro:;

H2O : 125 mg/mL (579.70 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.6376 mL 23.1879 mL 46.3757 mL
5 mM 0.9275 mL 4.6376 mL 9.2751 mL
10 mM 0.4638 mL 2.3188 mL 4.6376 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. Späte AK, et al. Expanding the scope of cyclopropene reporters for the detection of metabolically engineered glycoproteins by Diels-Alder reactions. Beilstein J Org Chem. 2014;10:2235-2242. Published 2014 Sep 22.

荧光染料7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

发表于由

荧光染料Dye Reagents 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester;

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester 是一种荧光生物试剂，可用于胺反应性标记。

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester Chemical Structure

CAS No. : 113721-87-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a bioReagent, suitable for fluorescence, can be used for amine-reactive labeling.

分子量

330.29

Formula

C16H14N2O6
CAS 号

113721-87-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

荧光染料7-Amino-4-(trifluoromethyl)coumarin(Synonyms: 香豆素151 Coumarin 151 AFC)

发表于由

荧光染料Dye Reagents 7-Amino-4-(trifluoromethyl)coumarin;(Synonyms: 香豆素151; Coumarin 151; AFC) 纯度: 99.10%

7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是荧光标记物，可用来灵敏的检测蛋白酶。它的激发和发射波长分别为400和500 nm。

7-Amino-4-(trifluoromethyl)coumarinamp;;(Synonyms: 香豆素151; Coumarin 151; AFC)

7-Amino-4-(trifluoromethyl)coumarin Chemical Structure

CAS No. : 53518-15-3

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
100 mg ￥660 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

7-Amino-4-(trifluoromethyl)coumarin 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Fragment Library
  • Medicine Food Homology Compound Library

生物活性

7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.

体外研究
(In Vitro)

Amino acid and peptide derivatives of 7-amino-4-(trifluoromethyl)coumarin are used to monitor peptidase activities. Caspase activation is measured using the fluorogenic compound N-acetyl-asp-glu-val-asp-7-Amino-4-(trifluoromethyl)coumarin (Ac-DEVD-AFC). This substrate rapidly enters cells where it is efficiently cleaved at the aspartate residue by specific caspases, yielding the fluorescent compound 7-Amino-4-(trifluoromethyl)coumarin (AFC). Following cell disruption, released 7-Amino-4-(trifluoromethyl)coumarin is separated on HPLC and detected by fluorescence. The appearance of 7-Amino-4-(trifluoromethyl)coumarin in cells is blocked by the pancaspase inhibitor benzyloxycarbonyl-val-ala-asp-fluoromethylketone, thus establishing that intracellular caspases are responsible for the cleavage[1]. γ-glutamyl-7-amino-4-(trifluoro-methyl)coumarin is synthesized and used as a substrate for fluirimetric assay of γ-gluta-myltranspeptidase. The reaction product 7-amino-4-(trifluoromethyl)coumarin is fluorescent at neutral pH values and with excitation and emission wavelengths of 400 and 490 nm, respectively, concentration is linearly related to fluorescence over the range of 10 to 300 pmol/3 mL reaction mixture[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

229.16

Formula

C10H6F3NO2
CAS 号

53518-15-3
中文名称

香豆素151；7-氨基-4-氟甲醇
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
溶解性数据
In Vitro:;

DMSO : 100 mg/mL (436.38 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.3638 mL 21.8188 mL 43.6376 mL
5 mM 0.8728 mL 4.3638 mL 8.7275 mL
10 mM 0.4364 mL 2.1819 mL 4.3638 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (10.91 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (10.91 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Tao Z, et al. Caspase activation by anticancer drugs: the caspase storm. Mol Pharm. 2007 Jul-Aug;4(4):583-95.

    [2]. White IN, et al. A continuous fluorometric assay for gamma-glutamyltranspeptidase. Anal Biochem. 1996 Jan 1;233(1):71-5.

荧光染料7-Amino-4-(trifluoromethyl)coumarin(Synonyms: 香豆素151 Coumarin 151 AFC)

发表于由

荧光染料Dye Reagents 7-Amino-4-(trifluoromethyl)coumarin;(Synonyms: 香豆素151; Coumarin 151; AFC) 纯度: 99.10%

7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) 是荧光标记物，可用来灵敏的检测蛋白酶。它的激发和发射波长分别为400和500 nm。

7-Amino-4-(trifluoromethyl)coumarin(Synonyms: 香豆素151; Coumarin 151; AFC)

7-Amino-4-(trifluoromethyl)coumarin Chemical Structure

CAS No. : 53518-15-3

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
100 mg ￥660 In-stock
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

7-Amino-4-(trifluoromethyl)coumarin 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • Fragment Library
  • Medicine Food Homology Compound Library

生物活性

7-Amino-4-(trifluoromethyl)coumarin (Coumarin 151) is a fluorescent marker for the sensitive detection of proteinases. The excitation and emission wavelengths are 400 and 490 nm, respectively.

体外研究
(In Vitro)

Amino acid and peptide derivatives of 7-amino-4-(trifluoromethyl)coumarin are used to monitor peptidase activities. Caspase activation is measured using the fluorogenic compound N-acetyl-asp-glu-val-asp-7-Amino-4-(trifluoromethyl)coumarin (Ac-DEVD-AFC). This substrate rapidly enters cells where it is efficiently cleaved at the aspartate residue by specific caspases, yielding the fluorescent compound 7-Amino-4-(trifluoromethyl)coumarin (AFC). Following cell disruption, released 7-Amino-4-(trifluoromethyl)coumarin is separated on HPLC and detected by fluorescence. The appearance of 7-Amino-4-(trifluoromethyl)coumarin in cells is blocked by the pancaspase inhibitor benzyloxycarbonyl-val-ala-asp-fluoromethylketone, thus establishing that intracellular caspases are responsible for the cleavage[1]. γ-glutamyl-7-amino-4-(trifluoro-methyl)coumarin is synthesized and used as a substrate for fluirimetric assay of γ-gluta-myltranspeptidase. The reaction product 7-amino-4-(trifluoromethyl)coumarin is fluorescent at neutral pH values and with excitation and emission wavelengths of 400 and 490 nm, respectively, concentration is linearly related to fluorescence over the range of 10 to 300 pmol/3 mL reaction mixture[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

229.16

Formula

C10H6F3NO2
CAS 号

53518-15-3
中文名称

香豆素151；7-氨基-4-氟甲醇
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
溶解性数据
In Vitro:;

DMSO : 100 mg/mL (436.38 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.3638 mL 21.8188 mL 43.6376 mL
5 mM 0.8728 mL 4.3638 mL 8.7275 mL
10 mM 0.4364 mL 2.1819 mL 4.3638 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (10.91 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (10.91 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Tao Z, et al. Caspase activation by anticancer drugs: the caspase storm. Mol Pharm. 2007 Jul-Aug;4(4):583-95.

    [2]. White IN, et al. A continuous fluorometric assay for gamma-glutamyltranspeptidase. Anal Biochem. 1996 Jan 1;233(1):71-5.

荧光染料7-Amino-4-methylcoumarin-3-acetic acid(Synonyms: 7-氨基-4-甲基-3-香豆素醋酸)

发表于由

荧光染料Dye Reagents 7-Amino-4-methylcoumarin-3-acetic acid;(Synonyms: 7-氨基-4-甲基-3-香豆素醋酸)

7-Amino-4-methylcoumarin-3-acetic acid 是一种荧光蛋白质标记剂。7-Amino-4-methylcoumarin-3-acetic acid 在紫外光 (350 nm) 激活时在蓝色区域 (440-460 nm) 发光。

7-Amino-4-methylcoumarin-3-acetic acid(Synonyms: 7-氨基-4-甲基-3-香豆素醋酸)

7-Amino-4-methylcoumarin-3-acetic acid Chemical Structure

CAS No. : 106562-32-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

7-Amino-4-methylcoumarin-3-acetic acid is a fluorescent protein labelling agent. 7-Amino-4-methylcoumarin-3-acetic acid emits in the blue region (440-460 nm) on activation with UV light (350 nm)[1].

分子量

233.22

Formula

C12H11NO4
CAS 号

106562-32-7
中文名称

7-氨基-4-甲基-3-香豆素醋酸
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Khalfan H, et al. Aminomethyl coumarin acetic acid: a new fluorescent labelling agent for proteins. Histochem J. 1986;18(9):497-499.

N-Acetyl-D-glucosamine(Synonyms: N-乙酰-D-氨基葡萄糖; N-Acetyl-2-amino-2-deoxy-D-glucose)

发表于由

天然产物 糖类和糖苷 Saccharides and Glycosides

N-Acetyl-D-glucosamine;(Synonyms: N-乙酰-D-氨基葡萄糖; N-Acetyl-2-amino-2-deoxy-D-glucose) 纯度: ge;97.0%

N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) 是葡萄糖的单糖衍生物。

N-Acetyl-D-glucosamine(Synonyms: N-乙酰-D-氨基葡萄糖; N-Acetyl-2-amino-2-deoxy-D-glucose)

N-Acetyl-D-glucosamine Chemical Structure

CAS No. : 7512-17-6

规格 价格 是否有货 数量
10;mM;*;1 mL in DMSO ￥500 In-stock
500 mg ￥400 In-stock
1 g ￥500 In-stock
5 g ; 询价 ;
10 g ; 询价 ;

* Please select Quantity before adding items.

N-Acetyl-D-glucosamine 相关产品

bull;相关化合物库:

  • Covalent Screening Library Plus
  • Natural Product Library Plus
  • Drug Repurposing Compound Library Plus
  • Clinical Compound Library Plus
  • Bioactive Compound Library Plus
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Clinical Compound Library
  • Human Endogenous Metabolite Compound Library
  • Drug Repurposing Compound Library
  • Covalent Screening Library
  • Anti-COVID-19 Compound Library
  • Traditional Chinese Medicine Monomer Library
  • FDA Approved amp; Pharmacopeial Drug Library
  • Gut Microbial Metabolite Library
  • Microbial Metabolite Library
  • Food-Sourced Compound Library

生物活性

N-Acetyl-D-Glucosamine (N-Acetyl-2-amino-2-deoxy-D-glucose) is a monosaccharide derivative of glucose.

IC50 Target

Human Endogenous Metabolite

;

Microbial Metabolite

;

Clinical Trial

分子量

221.21

Formula

C8H15NO6
CAS 号

7512-17-6
中文名称

N-乙酰-D-氨基葡萄糖
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20deg;C, stored under nitrogen

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (stored under nitrogen)
溶解性数据
In Vitro:;

DMSO : 130 mg/mL (587.68 mM; Need ultrasonic)

H2O : 100 mg/mL (452.06 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.5206 mL 22.6030 mL 45.2059 mL
5 mM 0.9041 mL 4.5206 mL 9.0412 mL
10 mM 0.4521 mL 2.2603 mL 4.5206 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 3.25 mg/mL (14.69 mM); Clear solution

    此方案可获得 ≥ 3.25 mg/mL (14.69 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3.25 mg/mL (14.69 mM); Clear solution

    此方案可获得 ≥ 3.25 mg/mL (14.69 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂：;10% DMSO ;; 90% corn oil

    Solubility: ≥ 3.25 mg/mL (14.69 mM); Clear solution

    此方案可获得 ≥ 3.25 mg/mL (14.69 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Slawson C, et al. O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks. J Cell Biochem. 2006 Jan 1;97(1):71-83.

7-Amino-4-methylcoumarin(Synonyms: 7-氨基-4-甲基香豆素 Coumarin 120 AMC)

发表于由

7-Amino-4-methylcoumarin;(Synonyms: 7-氨基-4-甲基香豆素; Coumarin 120; AMC) 纯度: 99.06%

7-amino-4-methylcoumarin (Coumarin 120) 被用作许多丝氨酸蛋白酶的荧光探针。

7-Amino-4-methylcoumarinamp;;(Synonyms: 7-氨基-4-甲基香豆素; Coumarin 120; AMC)

7-Amino-4-methylcoumarin Chemical Structure

CAS No. : 26093-31-2

规格 价格 是否有货 数量
Free Sample (0.1-0.5 mg) ; Apply now ;
10;mM;*;1 mL in DMSO ￥605 In-stock
50 mg ￥550 In-stock
100 mg ; 询价 ;
200 mg ; 询价 ;

* Please select Quantity before adding items.

7-Amino-4-methylcoumarin 相关产品

bull;相关化合物库:

  • Fragment Library
  • Bioactive Compound Library Plus

生物活性

7-amino-4-methylcoumarin (Coumarin 120) has been used as a fluorogenic probe for many serine proteases.

分子量

175.18

Formula

C10H9NO2
CAS 号

26093-31-2
中文名称

7-氨基-4-甲基香豆素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4deg;C, protect from light

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)
溶解性数据
In Vitro:;

DMSO : 100 mg/mL (570.84 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.7084 mL 28.5421 mL 57.0841 mL
5 mM 1.1417 mL 5.7084 mL 11.4168 mL
10 mM 0.5708 mL 2.8542 mL 5.7084 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂：;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (14.27 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (14.27 mM，饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂：;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (14.27 mM); Suspended solution; Need ultrasonic

    此方案可获得 2.5 mg/mL (14.27 mM) 的均匀悬浊液，悬浊液可用于口服和腹腔注射。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
  • 3.

    请依序添加每种溶剂：;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (14.27 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (14.27 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献

  • [1]. Choi MG, et al. A fluorogenic method for measuring enteropeptidase activity: spectral shift in the emission of GD4K-conjugated 7-amino-4-methylcoumarin.BMB Rep. 2011 Jul;44(7):458-61.

9-Amino-6-chloro-2-methoxyacridine

发表于由

9-Amino-6-chloro-2-methoxyacridine;

9-Amino-6-chloro-2-methoxyacridine 是一种 pH 敏感的荧光探针。9-Amino-6-chloro-2-methoxyacridine 经常用于测量特定底物通过假定的 H+/溶质反转运系统穿过液泡膜时液泡 pH 值的变化。

9-Amino-6-chloro-2-methoxyacridineamp;;

9-Amino-6-chloro-2-methoxyacridine Chemical Structure

CAS No. : 3548-09-2

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

9-Amino-6-chloro-2-methoxyacridine is a pH sensitive fluorescent probe. 9-Amino-6-chloro-2-methoxyacridine has been frequently used to measure changes in vacuolar pH when a specific substrate crosses the tonoplast through a putative H+/solute antiport system[1].

分子量

258.70

Formula

C14H11ClN2O
CAS 号

3548-09-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Carqueijeiro I, et al. Analytical and Fluorimetric Methods for the Characterization of the Transmembrane Transport of Specialized Metabolites in Plants. Methods Mol Biol. 2016;1405:121-135.