Cholecystokinin Octapeptide, desulfated(Synonyms: CCK Octapeptide, desulfated)

Cholecystokinin Octapeptide, desulfated;(Synonyms: CCK Octapeptide, desulfated)

Cholecystokinin Octapeptide, desulfated 是一种合成的脱硫的八肽胆囊收缩素 (CCK)。

Cholecystokinin Octapeptide, desulfatedamp;;(Synonyms: CCK Octapeptide, desulfated)

Cholecystokinin Octapeptide, desulfated Chemical Structure

CAS No. : 25679-24-7

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Cholecystokinin Octapeptide, desulfated 的其他形式现货产品:

Cholecystokinin Octapeptide, desulfated TFA

生物活性

Cholecystokinin Octapeptide, desulfated is a synthetic desulfated octapeptides of cholecystokinin (CCK)[1].

分子量

1063.21

Formula

C49H62N10O13S2

CAS 号

25679-24-7

Sequence

Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2

Sequence Shortening

DYMGWMDF-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. L R Johnson, et al. Effect of sulfation on the gastrointestinal actions of caerulein. Gastroenterology. 1970 Feb;58(2):208-16.

Caerulein, desulfated

Caerulein, desulfated;

Caerulein, desulfated 是脱硫后的Caerulein。Caerulein 是一种十肽,与胃泌素和胆囊收缩素 (CCK) 具有相同的五个羧基末端氨基酸。

Caerulein, desulfatedamp;;

Caerulein, desulfated Chemical Structure

CAS No. : 20994-83-6

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

生物活性

Caerulein, desulfated is the desulfurated form of Caerulein. Caerulein is a decapeptide having the same five carboxyl-terminal amino acids as gastrin and cholecystokinin (CCK)[1].

分子量

1272.34

Formula

C58H73N13O18S

CAS 号

20994-83-6

Sequence

{Glp}-Gln-Asp-Tyr-Thr-Gly-Trp-Met-Asp-Phe-NH2

Sequence Shortening

{Glp}-QDYTGWMDF-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Johnson LR, et al. Effect of sulfation on the gastrointestinal actions of caerulein. Gastroenterology. 1970 Feb;58(2):208-16.

Caerulein, desulfated TFA

Caerulein, desulfated TFA;

Caerulein, desulfated TFA 是脱硫后的Caerulein。Caerulein 是一种十肽,与胃泌素和胆囊收缩素 (CCK) 具有相同的五个羧基末端氨基酸。

Caerulein, desulfated TFAamp;;

Caerulein, desulfated TFA Chemical Structure

规格 价格 是否有货
1 mg ¥870 询问价格 货期
5 mg ¥2600 询问价格 货期
10 mg ¥4500 询问价格 货期

* Please select Quantity before adding items.

生物活性

Caerulein, desulfated TFA is the desulfurated form of Caerulein. Caerulein is a decapeptide having the same five carboxyl-terminal amino acids as gastrin and cholecystokinin (CCK)[1].

分子量

1386.36

Formula

C60H74F3N13O20S

Sequence

{Glp}-Gln-Asp-Tyr-Thr-Gly-Trp-Met-Asp-Phe-NH2

Sequence Shortening

{Glp}-QDYTGWMDF-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro:;

DMSO : 100 mg/mL (72.13 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.7213 mL 3.6066 mL 7.2131 mL
5 mM 0.1443 mL 0.7213 mL 1.4426 mL
10 mM 0.0721 mL 0.3607 mL 0.7213 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂:;10% DMSO ;; 40% PEG300 ;; 5% Tween-80 ;; 45% saline

    Solubility: ≥ 2.5 mg/mL (1.80 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (1.80 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂:;10% DMSO ;; 90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (1.80 mM); Suspended solution; Need ultrasonic

    此方案可获得 2.5 mg/mL (1.80 mM) 的均匀悬浊液,悬浊液可用于口服和腹腔注射。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂:;10% DMSO ;; 90% corn oil

    Solubility: ≥ 2.5 mg/mL (1.80 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (1.80 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. Johnson LR, et al. Effect of sulfation on the gastrointestinal actions of caerulein. Gastroenterology. 1970 Feb;58(2):208-16.

Cholecystokinin Octapeptide, desulfated TFA(Synonyms: CCK Octapeptide, desulfated TFA)

Cholecystokinin Octapeptide, desulfated TFA (Synonyms: CCK Octapeptide, desulfated TFA) 纯度: 99.17%

Cholecystokinin Octapeptide, desulfated TFA 是一种合成的脱硫的八肽胆囊收缩素 (CCK)。

Cholecystokinin Octapeptide, desulfated TFA&nbsp;(Synonyms: CCK Octapeptide, desulfated TFA)

Cholecystokinin Octapeptide, desulfated TFA Chemical Structure

CAS No. : 171486-94-5

规格 价格 是否有货 数量
1 mg ¥1400 In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Cholecystokinin Octapeptide, desulfated TFA 相关产品

相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Cholecystokinin Octapeptide, desulfated TFA is a synthetic desulfated octapeptides of Cholecystokinin (CCK)[1].

分子量

1177.23

Formula

C51H63F3N10O15S2

CAS 号

171486-94-5

Sequence

Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2

Sequence Shortening

DYMGWMDF-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro: 

DMSO : 50 mg/mL (42.47 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (ultrasonic) (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.8495 mL 4.2473 mL 8.4945 mL
5 mM 0.1699 mL 0.8495 mL 1.6989 mL
10 mM 0.0849 mL 0.4247 mL 0.8495 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (2.12 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.12 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.12 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (2.12 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 MCE 网站选购。
参考文献
  • [1]. L R Johnson, et al. Effect of sulfation on the gastrointestinal actions of caerulein. Gastroenterology. 1970 Feb;58(2):208-16.

  • [1]. L R Johnson, et al. Effect of sulfation on the gastrointestinal actions of caerulein. Gastroenterology. 1970 Feb;58(2):208-16.