Zinquin ethyl ester is a zinc ion-specific fluorophore. Zinquin ethyl ester is a lipophilic, zinc-sensitive, fluorescent derivative of Zinquin that is able to penetrate cell membranes[1].
分子量
414.47
Formula
C21H22N2O5S
CAS 号
181530-09-6
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Kevyn E Merten, et al. Zinc inhibits doxorubicin-activated calcineurin signal transduction pathway in H9c2 embryonic rat cardiac cells. Exp Biol Med (Maywood). 2007 May;232(5):682-9.
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2].
分子量
222.24
Formula
C12H14O4
CAS 号
4046-02-0
中文名称
阿魏酸乙酯
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8.
[2]. Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58.
(E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic and anti-microbial effects. (E)-Ethyl p-methoxycinnamate inhibits COX-1 and COX-2 in vitro with IC50s of 1.12 and 0.83 μM, respectively[1].
IC50 & Target[1]
COX-1
1.12 μM (IC50)
COX-2
0.83 μM (IC50)
分子量
206.24
Formula
C12H14O3
CAS 号
24393-56-4
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. Umar MI, et al. Bioactivity-guided isolation of ethyl-p-methoxycinnamate, an anti-inflammatory constituent, from Kaempferia galangal L. extracts. Molecules. 2012 Jul 23;17(7):8720-34.
7-Ethoxyresorufin (Resorufin ethyl ether) 是细胞色素 P450 (尤其是 CYP1A1) 的荧光底物和竞争性抑制剂。7-Ethoxyresorufin 也抑制 NO 合酶 (NO synthase)。
7-Ethoxyresorufin Chemical Structure
CAS No. : 5725-91-7
规格
价格
是否有货
数量
10;mM;*;1 mL in DMSO
¥770
In-stock
5 mg
¥700
In-stock
10 mg
¥1200
In-stock
25 mg
¥2500
In-stock
50 mg
¥4500
In-stock
100 mg
¥7500
询价
200 mg
;
询价
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500 mg
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询价
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7-Ethoxyresorufin 相关产品
bull;相关化合物库:
Bioactive Compound Library Plus
Immunology/Inflammation Compound Library
Metabolism/Protease Compound Library
Anti-Aging Compound Library
Antioxidants Compound Library
Oxygen Sensing Compound Library
Neuroprotective Compound Library
Angiogenesis Related Compound Library
生物活性
7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2].
分子量
241.24
Formula
C14H11NO3
CAS 号
5725-91-7
中文名称
乙氧基试卤灵;7-乙氧基-3H-吩恶嗪-3-酮
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder
-20deg;C
3 years
In solvent
-80deg;C
6 months
-20deg;C
1 month
溶解性数据
In Vitro:;
DMF : 2 mg/mL (8.29 mM; ultrasonic and warming and heat to 60°C)
[1]. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62.
[2]. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90.
Ethyl cinnamate is a fragrance ingredient used in many fragrance compounds. Ethyl cinnamate is a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues[1][2].
分子量
176.21
Formula
C11H12O2
CAS 号
103-36-6
中文名称
肉桂酸乙酯
运输条件
Room temperature in continental US; may vary elsewhere.
[1]. S P Bhatia, et al. Fragrance material review on ethyl cinnamate. Food Chem Toxicol. 2007;45 Suppl 1:S90-4.
[2]. Anika Klingberg, et al. Fully Automated Evaluation of Total Glomerular Number and Capillary Tuft Size in Nephritic Kidneys Using Lightsheet Microscopy. J Am Soc Nephrol. 2017 Feb;28(2):452-459.
p-Coumaric Acid Ethyl Ester is the ethyl ester of p-Coumaric acid[1]. p-Coumaric Acid is a potential immunosuppressive agent in treating autoimmune inflammatory diseases like rheumatoid arthritis[1].
分子量
192.21
Formula
C11H12O3
CAS 号
7362-39-2
中文名称
对香豆酸乙酯
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. T. Silva, et al. Hydroxycinnamic acid as a novel scaffold for the development of cyclooxygenase-2 inhibitors. RSC Advances. Issue 72, 2015.
[2]. Pragasam SJ, et al. Immunomodulatory and anti-inflammatory effect of p-coumaric acid, a common dietary polyphenol on experimental inflammation in rats. Inflammation. 2013 Feb;36(1):169-76.