Matairesinol

天然产物 天然产物苯丙素类 Phenylpropanoids

Matairesinol 

Matairesinol 在过敏性皮炎小鼠模型中具有抗过敏作用。Dfe 诱导的 NC/Nga 小鼠耳内 IL-4 和 IFN-γ mRNA 表达的变化可通过应用 Matairesinol 逆转。

Matairesinol

Matairesinol Chemical Structure

CAS No. : 580-72-3

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生物活性

Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-γ mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application[1].

IC50 & Target

Human Endogenous Metabolite

 

分子量

358.39

Formula

C20H22O6

CAS 号

580-72-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Sung YY, Lee AY, Kim HK. Forsythia suspensa fruit extracts and the constituent matairesinol confer anti-allergic effects in an allergic dermatitis mouse model. J Ethnopharmacol. 2016;187:49-56. 

Matairesinol monoglucoside(Synonyms: 异罗汉松脂苷)

天然产物 糖类和糖苷 Saccharides and Glycosides

Matairesinol monoglucoside;(Synonyms: 异罗汉松脂苷)

Matairesinol monoglucoside 是一种木脂素化合物,对 IFN-γ/STAT1IL-6/STAT3 信号通路具有较低的抑制活性,抑制率分别为 5.8% 和 7.0%。

Matairesinol monoglucoside(Synonyms: 异罗汉松脂苷)

Matairesinol monoglucoside Chemical Structure

CAS No. : 34446-06-5

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生物活性

Matairesinol monoglucoside, a lignan compound, exhibits low activity on IFN-γ/STAT1 and IL-6/STAT3 signaling pathways with inhibition ratio of 5.8% and 7.0%, respectively[1].

体外研究
(In Vitro)

Matairesinol monoglucoside (compound 3) has low activity on IFN-γ/STAT1 and IL-6/STAT3 signaling pathways with inhibition ratio of 5.8% and 7.0%, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

520.53

Formula

C26H32O11

CAS 号

34446-06-5

中文名称

异罗汉松脂苷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Liu XT, et, al. Active components with inhibitory activities on IFN-γ/STAT1 and IL-6/STAT3 signaling pathways from Caulis Trachelospermi. Molecules. 2014 Aug 5;19(8):11560-71.