Soyasaponin Ba(Synonyms: 大豆皂苷Ba)

天然产物 糖类和糖苷 Saccharides and Glycosides

Soyasaponin Ba;(Synonyms: 大豆皂苷Ba)

Soyasaponin Ba 是一种从菜豆类中分离出的大豆皂苷,能作为醛糖还原酶抑制剂 (ARI)

Soyasaponin Ba(Synonyms: 大豆皂苷Ba)

Soyasaponin Ba Chemical Structure

CAS No. : 114590-20-4

规格 价格 是否有货
5 mg ¥2020 询问价格 货期
10 mg ¥3430 询问价格 货期

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生物活性

Soyasaponin Ba is a soyasaponin isolated from Phaseolus vulgaris, acts as an aldose reductase inhibitors (ARI)[1].

分子量

959.12

Formula

C48H78O19

CAS 号

114590-20-4

中文名称

大豆皂苷Ba

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Balestri F, et al. Soyasaponins from Zolfino bean as aldose reductase differential inhibitors. J Enzyme Inhib Med Chem. 2019 Dec;34(1):350-360.

AE 100、AE 98-whatman BA诊断膜

产品型号AE 100、AE 98

品       牌沃特曼

厂商性质代理商

产品简介

whatman BA诊断膜是由纯硝酸纤维素构成的无底衬膜。这些小孔径的膜拥有很大的表面积,很高的蛋白吸附量。

详情介绍

渗滤法诊断膜?用来做渗滤测试的膜通常就是覆盖有硝酸纤维素膜的纸。膜直接覆盖在高质量纤维滤纸的表面。简化了生产工艺,降低了不同材质之间接触不良造成的检测问题的可能性,可以使用小孔径的不带衬的膜。当然,他们需要被非常仔细地包裹以保证膜和滤纸之间的紧密结合。

BA诊断膜是由纯硝酸纤维素构成的无底衬膜。这些小孔径的膜拥有很大的表面积,很高的蛋白吸附量。

功能和优点

·为纵向流测试制造
消除由毛细上升引起的问题

·较小的孔径
结果准确,更低的非特异性吸附,更高的灵敏度

·增大的表面积
高结合能力,高灵敏度,得到非常好的信噪比。

·100%纯硝酸纤维素
保证了的吸附能力

AE 100、AE 98-whatman BA诊断膜?

BA-S 83, BA-S 85-Whatman 沃特曼 Optitran 加强型硝酸纤维素膜

产品型号BA-S 83, BA-S 85

品       牌沃特曼

厂商性质代理商

产品简介

Whatman 沃特曼 Optitran 加强型硝酸纤维素膜是在100%纯硝酸纤维素膜中插入聚酯非纺织材料制成,这种聚酯的支持物并不影响转移条件和效果,同时具备了更强的操作强度,允许反复多重杂交。 Optitran硝酸纤维素膜拥有极低的非特异性结合力,从而保证了更高的灵敏度。使用标准的硝酸纤维素加工流程制成的膜,使用时无需严苛的洗膜和封膜条件。

详情介绍

名称 : Whatman 沃特曼 Optitran 加强型硝酸纤维素膜

型号 :BA-S 83, BA-S 85

Whatman 沃特曼 Optitran 加强型硝酸纤维素膜, BA-S 83, BA-S 85

详细描述

, BA-S 83, BA-S 85

Whatman 加强型硝酸纤维素膜
Optitran?膜是在100%纯硝酸纤维素膜中插入聚酯非纺织材料制成,这种聚酯的支持物并不影响转移条件和效果,同时具备了更强的操作强度,允许反复多重杂交。

Optitran硝酸纤维素膜拥有极低的非特异性结合力,从而保证了更高的灵敏度。使用标准的硝酸纤维素加工流程制成的膜,使用时无需严苛的洗膜和封膜条件。

Optitran膜集合柔韧性、高强度和的信噪比于一体,尤其适合反复杂交实验。

Optitran硝酸纤维素支持型膜灵敏度高,机械强度好,帮您省去更多花费。

Optitran结合能力:75~90μg/cm2,可高压灭菌(液体冷循环)

BA-S 83, BA-S 85-Whatman 沃特曼 Optitran 加强型硝酸纤维素膜

, BA-S 83, BA-S 85

10439391, 10439380, 10439394, 10439396, 10439116, 10439126, 10439191, 10439180, 10439194, 10439196

, BA-S 83, BA-S 85

BA 1

BA 1;

BA 1 是一种 bombesin (BB) 受体家族激动剂。BA 1 与 Bombesin 受体亚型 3 (BRS3),胃泌素释放肽受体 (GRPR),神经调节素 B 受体 (NMBR) 高亲和力结合,IC50 分别为 6、0.4、2.5 nM 。

BA 1amp;;

BA 1 Chemical Structure

CAS No. : 183241-31-8

规格 是否有货
100 mg ; 询价 ;
250 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

BA 1 的其他形式现货产品:

BA 1 TFA

生物活性

BA 1 is a potent agonist for the bombesin (BB) family of receptors. BA 1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].

体外研究
(In Vitro)

BA 1 (0.1 μM) significantly increases FAK tyrosine phosphorylation in BRS-3 transfected NCI-H1299 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1133.30

Formula

C9H19FN3O2VWY

CAS 号

183241-31-8

Sequence Shortening

YQWAV{Bal}HF{Nle}-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.

Abaloparatide TFA(Synonyms: 阿巴洛肽 BA 058 TFA BIM 44058 TFA)

Abaloparatide TFA;(Synonyms: 阿巴洛肽; BA 058 TFA; BIM 44058 TFA) 纯度: 96.11%

Abaloparatide TFA (BA 058 TFA) 是一种甲状旁腺激素受体 1 PTHR1 类似物,是 PTHR1 信号通路的有效和选择性激活剂。Abaloparatide TFA 增强 MC3T3-E1 成骨细胞的 Gs/cAMP 信号传导 (EC50 为 0.3 nM) 和 β-arrestin 的募集 (EC50 为 0.9 nM)。

Abaloparatide TFA (Synonyms: 阿巴洛肽; BA 058 TFA; BIM 44058 TFA)

Abaloparatide TFA Chemical Structure

规格 价格 是否有货 数量
1 mg ¥1200 In-stock
5 mg ¥3500 In-stock
10 mg ¥5500 In-stock
25 mg ¥9900 In-stock
50 mg ¥16500 In-stock
100 mg ¥22500 询价
200 mg ; 询价 ;
500 mg ; 询价 ;

* Please select Quantity before adding items.

Abaloparatide TFA 相关产品

相关化合物库:

  • Drug Repurposing Compound Library Plus
  • FDA-Approved Drug Library Plus
  • FDA-Approved Drug Library Mini
  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Abaloparatide TFA (BA 058 TFA) is a parathyroid hormone receptor 1 (PTHR1) analogue selected to be a potent and selective activator of the PTHR1 signaling pathway. Abaloparatide TFA enhances Gs/cAMP signaling (EC50 of 0.3 nM) and β-arrestin recruitment (EC50 of 0.9 nM) in MC3T3-E1 osteoblast cells[1][2].

IC50 & Target

Parathyroid hormone receptor 1 (PTHR1)[1]

体外研究
(In Vitro)

MC3T3-E1 osteoblast cells are treated with 0.01-100 nM of Abaloparatide for 40 min at 37 ℃ in the presence of 0.5 mM IBMX. The results reveals that exposure of cells to Abaloparatide caused a robust elevation of intracellular cAMP levels. Abaloparatide treatment results in a 2.3-fold decrease in EC50 value for cAMP formation compared to teriparatide (EC50s of 0.3 nM and 0.7 nM, respectively)[1].
A dose-dependent stimulation of β-arrestin/PTHR1 interaction is demonstrated by abaloparatide. Consistently, the calculates the EC50 value for abaloparatide is 1.6-fold lower than that of teriparatide (EC50s of 0.9 nM and 1.5 nM, respectively)[1].
Abaloparatide efficiently induces a dose-dependent stimulation of PTHR1 internalization with a dose as low as 0.1 nM and reaches maximum stimulation at 100 nM concentration. The EC50 value of 0.8 nM for Abaloparatide[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Abaloparatide (1-25 µg/kg; subcutaneous injection; daily; for 12 months; female Sprague-Dawley rats) treatment increases biochemical bone formation markers, histomorphometric indices of bone formation on trabecular, endocortical, and periosteal surfaces. Abaloparatide induces substantial increases in trabecular bone volume and density and improvements in trabecular microarchitecture. Abaloparatide stimulates periosteal expansion and endocortical bone apposition at the tibial diaphysis, leading to marked increases in cortical bone volume and density. Whole-body bone mineral density (BMD) is increasing 25% after 12 months of abaloparatide (25 μg/kg) in osteopenic ovariectomized (OVX) rats[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female Sprague-Dawley rats (age 22 weeks)[2]
Dosage: 1 µg/kg, 5 µg/kg, 25 µg/kg
Administration: Subcutaneous injection; daily; for 12 months
Result: Increased biochemical bone formation markers, histomorphometric indices of bone formation on trabecular, endocortical, and periosteal surfaces. Induced substantial increases in trabecular bone volume and density and improvements in trabecular microarchitecture. Stimulated periosteal expansion and endocortical bone apposition at the tibial diaphysis, leading to marked increases in cortical bone volume and density. Whole-body bone mineral density (BMD) was increasing 25%.

Clinical Trial

分子量

4074.61

Formula

C176H301N56F3O51

Sequence

Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-{Aib}-Lys-Leu-His-Thr-Ala-NH2

Sequence Shortening

AVSEHQLLHDKGKSIQDLRRRELLEKLL-{Aib}-KLHTA-NH2

中文名称

安巴洛他定; 阿巴洛肽; 阿达帕拉肽

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light, stored under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro:;

H2O : ≥ 50 mg/mL (12.27 mM)

* “≥” means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.2454 mL 1.2271 mL 2.4542 mL
5 mM 0.0491 mL 0.2454 mL 0.4908 mL
10 mM 0.0245 mL 0.1227 mL 0.2454 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

参考文献
  • [1]. Sahbani K, et al. Abaloparatide exhibits greater osteoanabolic response and higher cAMP stimulation and β-arrestin recruitment than teriparatide. Physiol Rep. 2019 Oct;7(19):e14225.

    [2]. Varela A, et al. One Year of Abaloparatide, a Selective Activator of the PTH1 Receptor, Increased Bone Formation and Bone Mass in Osteopenic Ovariectomized Rats Without Increasing Bone Resorption. J Bone Miner Res. 2017 Jan;32(1):24-33.

BA 1 TFA

BA 1 TFA; 纯度: 99.65%

BA 1 TFA 是一种 bombesin (BB) 受体家族激动剂。BA 1 与 Bombesin 受体亚型 3 (BRS3),胃泌素释放肽受体 (GRPR),神经调节素 B 受体 (NMBR) 高亲和力结合,IC50 分别为 6、0.4、2.5 nM 。

BA 1 TFAamp;;

BA 1 TFA Chemical Structure

规格 价格 是否有货 数量
5 mg ¥2000 In-stock
10 mg ; 询价 ;
50 mg ; 询价 ;

* Please select Quantity before adding items.

BA 1 TFA 相关产品

bull;相关化合物库:

  • Bioactive Compound Library Plus
  • GPCR/G Protein Compound Library
  • Anti-Cancer Compound Library
  • Targeted Diversity Library
  • Peptide Library

生物活性

BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC50s of 6, 0.4, 2.5 nM[1].

体外研究
(In Vitro)

BA1 (0.1 μM) significantly increases FAK tyrosine phosphorylation in BRS-3 transfected NCI-H1299 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1247.32

Formula

C59H77F3N14O13

Sequence Shortening

YQWAV{Bal}HF{Nle}-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light

Powder -80deg;C 2 years
-20deg;C 1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (protect from light)

Solvent Solubility
In Vitro:;

H2O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

; Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.;;Recommended solution:

Overall charge of peptide Details
Negative (lt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, add NH4OH (lt;50 μL).
3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0) 1.;;Try to dissolve the peptide in water first.
2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
参考文献
  • [1]. Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.

york约克BA4000顺磁氧便携式氧分析仪

york约克BA4000顺磁氧便携式氧分析仪

york约克BA4000顺磁氧便携式氧分析仪

产品编号:
市场价:¥0.00
会员价:¥0.00
品牌:york约克
生产厂家:york约克

  • 产品概览
  • 技术参数
  • 订购信息
  • 相关资料
  • 相关产品

便携式氧分析仪适用于各种防爆环境的应用.并带有一系列可选项如气泵,流量计,警报设置点或带IP54保护的机箱,允许设备尽可能与实际应用场合配合.
    BA4000电源的连接内置在干加速器内,其高容量允许在无外部电源的情况下仍能独立工作一天.简易更换的精细过滤器保护测量池不受颗粒污染物的损害.对于湿样气的应用,我们提供便携式样气预处理系统TGAK.
    可选项气泵只推荐在大气压力和真空环境下使用,警报设置点可单独调节,用于显示偏离设定值的大小.连续的输出信号可设为a0-1V或0/4-20 mA 信号.校正可简单通过氮气和空气实现.

•顺磁哑铃球测量原理
• 4-20 mA 模拟输出
• 信赖度高Ó耐用性强的测量池
• 操作简单
• 快速精确的氧分析
• 不同范围可选
• 机箱IP54可选
• 电池运作

技术参数:

 

被测量成分:

信号输出

 

量程

0 … 10 Vol.% O 2

信号输出:

4…20 mA(max.400)

(根据订单)

0 … 25 Vol.% O 2

0…1V (min .1千欧)可选

(客户可选范围)

0 … 100 Vol.% O 2

显示

 

测量原理:

顺磁(哑铃球感应器)

显示:

LCD 液晶显示

特性

流量:

流量计

精度:

绝对0.1% O 2

量程:

0-10 NL/H空气

重复性:

±0.05% O 2

电源

响应时间:

T <10 S

电源:

230V,50/60HZ

零点飘移:

± 0.1 Vol.% O 2每周

115V,50/60HZ

量程飘移:

±1%量程/每周

内置电池:

12V,2.7Ah(操作时间大约14小时,不带其他可选项)

样气条件

结构数据

入口温度:

+5°C 40°C

外壳:

铝合金

入口压力:

至少:10mbar

防护等级:

IP20(标准)

最大:1.5bar

IP54(可选)

带内置泵

-5mbar

尺寸(H x W x D)

145X182X240mm(标准外壳)

样气流量

重量:

大约4.5KG

不带泵时:

大约120ml/min @min.压力

气体入口:

带玻璃纤维的过滤器

带内置泵:

大约30 l/h

气体连接:

6 mm OD

样气条件

4mm ID ,推上

露点:

在环境温度下至少5°C

直接与样气接触的部件:

PVDF,玻璃,SS1.4571,gold,viton,platinum-iridium,epoxyresin

粉尘:

8μ可更换过滤器,标准连接

校正要求

零气体:

氮气

量程气体:

空气或者瓶装的校正气体

环境条件

环境温度:

+ 10 °C 45 °C

存储温度:

25 °C 65 °C

相对温度:

平均值<75%

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4、DKW培养基(货号:D2470)
DKW培养基是由Driver和Kuniyuki于1954年开发的培养基,适用于包括胡桃木在内的多种木本植物组织培养。这种培养基是为节点外植体的芽增殖而开发的,在培养基中可添加4.5 uM和5 nM IBA,在苗期移栽到温室前,将苗期基部用5mM IBA浸种可促进苗期生根。

5、BG-11培养基(货号:B1511)
用途:常用于淡水蓝藻和绿藻的培养
使用量:1.68g/L
储存温度:2-6℃
配置方法:粉状培养基溶解后,用KOH或NaOH调节PH至8.0,然后高压灭菌,加入HEPES或TES缓冲PH。使用20mm HEPES与PCC 6803进行生物试验

6、BY-2培养基(货号:B1468)
为烟草BY-2悬浮细胞系培养而研发,烟草BY2细胞(Nicotiana tabacum L.cv Bright Yellow2,BY2)是一个非常重要且用途广泛的细胞系,它由Kato等于1972分离得到,在现有已建立的成熟植物细胞系中被认为是植物细胞中的Hela细胞,BY2细胞可以比较容易的转化外源基因,且转基因细胞团和悬浮培养细胞都较易得到。PhytoTech的BY-2培养基在原始配方中加入2,4-D(0.2mg/L)。该培养基也可以用于原生质体的培养。
使用浓度:4.63g/L
储存温度:2-8℃

Whatman硝酸纤维素膜 转印膜BA85 BA85


Whatman硝酸纤维素膜 转印膜BA85

Whatman硝酸纤维素膜 转印膜BA85 10401196 300mmX3m 0.45μm Whatman硝酸纤维素膜 转印膜BA85 应用于样品制备,微生物研究,水溶液过滤

WHATMAN  Protran硝酸纤维素膜  转印膜  BA85  

货号:转印膜10401196

应用于样品制备,微生物研究,水溶液过滤

孔径:0.45μm

尺寸:300mm X 3m

特征和优势

  孔径分布精准能改进表面捕获和分析

  溶出物水平低,保证样品的完整性

高结合力,低背景
  除了具有高结合能力以外,Protran硝酸纤维素膜本身产生的背景非常低,膜特有的表面性质保证了优异的信噪比,而同时却不需要严格的清洗条件。

小分子蛋白的高保留率
  Protran硝酸纤维素膜有多种孔径大小可供选择,使不同的应用都可以获得zui佳的效果。0.2μm孔径的Protran BA83硝酸 BA85硝酸纤维素膜是较大分子量样品和常规核酸研究的理想选择。0.1μm孔径的Protran BA79则用于分子量低于7kD的小分子蛋白转移。
 

Protran硝酸纤维素膜的一个主要优势在于,经实验证明,结合在Protran膜上的蛋白能够保持分子识别活性长达5年。
 

Protran杂交三明治组合
由1张预切的硝酸纤维素膜和2张3MM层析杂交纸组成的三明治包装,帮您节省更多的时间。这些膜都是用于杂交的质量zui好的NC膜——Protran BA83或者BA85。

Protran 硝酸纤维素膜的结合能力为80~150µg/cm2,可高压**(液体冷循环)