α-Factor Mating Pheromone, yeast TFA(Synonyms: Mating Factor α TFA)

α-Factor Mating Pheromone, yeast TFA;(Synonyms: Mating Factor α TFA)

α-Factor Mating Pheromone, yeast (TFA) 是一种十三肽，由 S. cerevisiae 的 α 细胞分泌产生，通过 Ste2p 受体起作用。

α-Factor Mating Pheromone, yeast TFA Chemical Structure

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生物活性

α-Factor Mating Pheromone, yeast (TFA) is a tridecapeptide secreted by S. cerevisiae α cells via Ste2p receptor^[1].

分子量

1798.02

Formula

C₈₄H₁₁₅N₂₀F₃O₁₉S

Sequence

Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

Sequence Shortening

WHWLQLKPGQPMY

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder	-80deg;C	2 years
	-20deg;C	1 year

*In solvent : -80deg;C, 6 months; -20deg;C, 1 month (sealed storage, away from moisture and light)

Solvent Solubility

In Vitro:;

H₂O

Peptide Solubility and Storage Guidelines:

1.;;Calculate the length of the peptide.

2.;;Calculate the overall charge of the entire peptide according to the following table:

;	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3.;;Recommended solution:

Overall charge of peptide	Details
Negative (lt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, add NH₄OH (lt;50 μL). 3.;;If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (gt;0)	1.;;Try to dissolve the peptide in water first. 2.;;If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3.;;If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1.;;Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2.;;For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

参考文献

[1]. [1]. Naider F, et al. The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors. Peptides. 2004 Sep;25(9):1441-63.

Euphorbia factor L8

上海金畔生物科技有限公司提供天然产物萜类及其苷类Terpenoids and Glycosides。

Euphorbia factor L8

Euphorbia factor L(8) 是大戟种子中的二萜。

Euphorbia factor L8 Chemical Structure

CAS No. : 218916-53-1

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生物活性	Euphorbia factor L(8) is a diterpenoid from the seeds of Euphorbia lathyris^[1].
分子量	523.62
Formula	C₃₀H₃₇NO₇
CAS 号	218916-53-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Jiao W, et al. Euphorbia factor L(8): a diterpenoid from the seeds of Euphorbia lathyris. Acta Crystallogr Sect E Struct Rep Online. 2007;64(Pt 1):o331. Published 2007 Dec 21.